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Anti-SLC39A5 monoclonal antibody
Pre-made anti-SLC39A5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SLC39A5/SLC39A5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1737-Ab-1/ GM-Tg-hg-IP1737-Ab-2 | Anti-Human SLC39A5 monoclonal antibody | Human |
| GM-Tg-rg-IP1737-Ab-1/ GM-Tg-rg-IP1737-Ab-2 | Anti-Rat SLC39A5 monoclonal antibody | Rat |
| GM-Tg-mg-IP1737-Ab-1/ GM-Tg-mg-IP1737-Ab-2 | Anti-Mouse SLC39A5 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1737-Ab-1/ GM-Tg-cynog-IP1737-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC39A5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1737-Ab-1/ GM-Tg-felg-IP1737-Ab-2 | Anti-Feline SLC39A5 monoclonal antibody | Feline |
| GM-Tg-cang-IP1737-Ab-1/ GM-Tg-cang-IP1737-Ab-2 | Anti-Canine SLC39A5 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1737-Ab-1/ GM-Tg-bovg-IP1737-Ab-2 | Anti-Bovine SLC39A5 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1737-Ab-1/ GM-Tg-equg-IP1737-Ab-2 | Anti-Equine SLC39A5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1737-Ab-1/ GM-Tg-hg-IP1737-Ab-2; GM-Tg-rg-IP1737-Ab-1/ GM-Tg-rg-IP1737-Ab-2; GM-Tg-mg-IP1737-Ab-1/ GM-Tg-mg-IP1737-Ab-2; GM-Tg-cynog-IP1737-Ab-1/ GM-Tg-cynog-IP1737-Ab-2; GM-Tg-felg-IP1737-Ab-1/ GM-Tg-felg-IP1737-Ab-2; GM-Tg-cang-IP1737-Ab-1/ GM-Tg-cang-IP1737-Ab-2; GM-Tg-bovg-IP1737-Ab-1/ GM-Tg-bovg-IP1737-Ab-2; GM-Tg-equg-IP1737-Ab-1/ GM-Tg-equg-IP1737-Ab-2 |
| Products Name | Anti-SLC39A5 monoclonal antibody |
| Format | mab |
| Target Name | SLC39A5 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SLC39A5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1737-Ag-1 | Recombinant multi-species S39A5/ SLC39A5/ LZT-Hs7 protein |
Target information
| Target ID | GM-IP1737 |
| Target Name | SLC39A5 |
| Gene ID | 283375,72002,362812,712131,481108,101097567,511782,100052215 |
| Gene Symbol and Synonyms | 1810013D05Rik,2010205A06Rik,LZT-Hs7,MYP24,SLC39A5,ZIP5 |
| Uniprot Accession | Q6ZMH5 |
| Uniprot Entry Name | S39A5_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000139540 |
| Target Classification | N/A |
The target: SLC39A5, gene name: SLC39A5, also named as LZT-Hs7, MYP24, ZIP5. The protein encoded by this gene belongs to the ZIP family of zinc transporters that transport zinc into cells from outside, and play a crucial role in controlling intracellular zinc levels. Zinc is an essential cofactor for many enzymes and proteins involved in gene transcription, growth, development and differentiation. Mutations in this gene have been associated with autosomal dominant high myopia (MYP24). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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