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Anti-SLC45A2 monoclonal antibody
Pre-made anti-SLC45A2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SLC45A2/SLC45A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1742-Ab-1/ GM-Tg-hg-IP1742-Ab-2 | Anti-Human SLC45A2 monoclonal antibody | Human |
| GM-Tg-rg-IP1742-Ab-1/ GM-Tg-rg-IP1742-Ab-2 | Anti-Rat SLC45A2 monoclonal antibody | Rat |
| GM-Tg-mg-IP1742-Ab-1/ GM-Tg-mg-IP1742-Ab-2 | Anti-Mouse SLC45A2 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1742-Ab-1/ GM-Tg-cynog-IP1742-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC45A2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1742-Ab-1/ GM-Tg-felg-IP1742-Ab-2 | Anti-Feline SLC45A2 monoclonal antibody | Feline |
| GM-Tg-cang-IP1742-Ab-1/ GM-Tg-cang-IP1742-Ab-2 | Anti-Canine SLC45A2 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1742-Ab-1/ GM-Tg-bovg-IP1742-Ab-2 | Anti-Bovine SLC45A2 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1742-Ab-1/ GM-Tg-equg-IP1742-Ab-2 | Anti-Equine SLC45A2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1742-Ab-1/ GM-Tg-hg-IP1742-Ab-2; GM-Tg-rg-IP1742-Ab-1/ GM-Tg-rg-IP1742-Ab-2; GM-Tg-mg-IP1742-Ab-1/ GM-Tg-mg-IP1742-Ab-2; GM-Tg-cynog-IP1742-Ab-1/ GM-Tg-cynog-IP1742-Ab-2; GM-Tg-felg-IP1742-Ab-1/ GM-Tg-felg-IP1742-Ab-2; GM-Tg-cang-IP1742-Ab-1/ GM-Tg-cang-IP1742-Ab-2; GM-Tg-bovg-IP1742-Ab-1/ GM-Tg-bovg-IP1742-Ab-2; GM-Tg-equg-IP1742-Ab-1/ GM-Tg-equg-IP1742-Ab-2 |
| Products Name | Anti-SLC45A2 monoclonal antibody |
| Format | mab |
| Target Name | SLC45A2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SLC45A2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1742-Ag-1 | Recombinant multi-species S45A2/ SLC45A2/ 1A1 protein |
Target information
| Target ID | GM-IP1742 |
| Target Name | SLC45A2 |
| Gene ID | 51151,22293,310152,698246,489236,100158246,538746,100068242 |
| Gene Symbol and Synonyms | 1A1,Aim-1,AIM1,blanc-sale,bls,Dbr,MATP,OCA4,SHEP5,SLC45A2,uw |
| Uniprot Accession | Q9UMX9 |
| Uniprot Entry Name | S45A2_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000164175 |
| Target Classification | N/A |
The target: SLC45A2, gene name: SLC45A2, also named as 1A1, AIM1, MATP, OCA4, SHEP5. This gene encodes a transporter protein that mediates melanin synthesis. The protein is expressed in a high percentage of melanoma cell lines. Mutations in this gene are a cause of oculocutaneous albinism type 4, and polymorphisms in this gene are associated with variations in skin and hair color. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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