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Anti-SLC46A3 monoclonal antibody
Pre-made anti-SLC46A3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SLC46A3/SLC46A3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1744-Ab-1/ GM-Tg-hg-IP1744-Ab-2 | Anti-Human SLC46A3 monoclonal antibody | Human |
| GM-Tg-rg-IP1744-Ab-1/ GM-Tg-rg-IP1744-Ab-2 | Anti-Rat SLC46A3 monoclonal antibody | Rat |
| GM-Tg-mg-IP1744-Ab-1/ GM-Tg-mg-IP1744-Ab-2 | Anti-Mouse SLC46A3 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1744-Ab-1/ GM-Tg-cynog-IP1744-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC46A3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1744-Ab-1/ GM-Tg-felg-IP1744-Ab-2 | Anti-Feline SLC46A3 monoclonal antibody | Feline |
| GM-Tg-cang-IP1744-Ab-1/ GM-Tg-cang-IP1744-Ab-2 | Anti-Canine SLC46A3 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1744-Ab-1/ GM-Tg-bovg-IP1744-Ab-2 | Anti-Bovine SLC46A3 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1744-Ab-1/ GM-Tg-equg-IP1744-Ab-2 | Anti-Equine SLC46A3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1744-Ab-1/ GM-Tg-hg-IP1744-Ab-2; GM-Tg-rg-IP1744-Ab-1/ GM-Tg-rg-IP1744-Ab-2; GM-Tg-mg-IP1744-Ab-1/ GM-Tg-mg-IP1744-Ab-2; GM-Tg-cynog-IP1744-Ab-1/ GM-Tg-cynog-IP1744-Ab-2; GM-Tg-felg-IP1744-Ab-1/ GM-Tg-felg-IP1744-Ab-2; GM-Tg-cang-IP1744-Ab-1/ GM-Tg-cang-IP1744-Ab-2; GM-Tg-bovg-IP1744-Ab-1/ GM-Tg-bovg-IP1744-Ab-2; GM-Tg-equg-IP1744-Ab-1/ GM-Tg-equg-IP1744-Ab-2 |
| Products Name | Anti-SLC46A3 monoclonal antibody |
| Format | mab |
| Target Name | SLC46A3 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SLC46A3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1744-Ag-1 | Recombinant multi-species S46A3/ SLC46A3/ FKSG16 protein |
Target information
| Target ID | GM-IP1744 |
| Target Name | SLC46A3 |
| Gene ID | 283537,71706,288454,712056,477324,101088541,781117,100062949 |
| Gene Symbol and Synonyms | 1200006F02Rik,FKSG16,RGD1307594,SLC46A3 |
| Uniprot Accession | Q7Z3Q1,Q5BK75,A5D7V7 |
| Uniprot Entry Name | S46A3_HUMAN,S46A3_RAT,S46A3_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000139508 |
| Target Classification | N/A |
The target: SLC46A3, gene name: SLC46A3, also named as FKSG16. The protein encoded by this gene is a member of a transmembrane protein family that transports small molecules across membranes. The encoded protein has been found in lysosomal membranes, where it can transport catabolites from the lysosomes to the cytoplasm. This protein has been shown to be an effective transporter of the cytotoxic drug maytansine, which is used in antibody-based targeting of cancer cells. [provided by RefSeq, Dec 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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