Anti-SMIM22 monoclonal antibody

Pre-made anti-SMIM22 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SMIM22/SMIM22 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1772-Ab-1/ GM-Tg-hg-IP1772-Ab-2Anti-Human SMIM22 monoclonal antibodyHuman
GM-Tg-rg-IP1772-Ab-1/ GM-Tg-rg-IP1772-Ab-2Anti-Rat SMIM22 monoclonal antibodyRat
GM-Tg-mg-IP1772-Ab-1/ GM-Tg-mg-IP1772-Ab-2Anti-Mouse SMIM22 monoclonal antibodyMouse
GM-Tg-cynog-IP1772-Ab-1/ GM-Tg-cynog-IP1772-Ab-2Anti-Cynomolgus/ Rhesus macaque SMIM22 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1772-Ab-1/ GM-Tg-felg-IP1772-Ab-2Anti-Feline SMIM22 monoclonal antibodyFeline
GM-Tg-cang-IP1772-Ab-1/ GM-Tg-cang-IP1772-Ab-2Anti-Canine SMIM22 monoclonal antibodyCanine
GM-Tg-bovg-IP1772-Ab-1/ GM-Tg-bovg-IP1772-Ab-2Anti-Bovine SMIM22 monoclonal antibodyBovine
GM-Tg-equg-IP1772-Ab-1/ GM-Tg-equg-IP1772-Ab-2Anti-Equine SMIM22 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1772-Ab-1/ GM-Tg-hg-IP1772-Ab-2; GM-Tg-rg-IP1772-Ab-1/ GM-Tg-rg-IP1772-Ab-2;
GM-Tg-mg-IP1772-Ab-1/ GM-Tg-mg-IP1772-Ab-2; GM-Tg-cynog-IP1772-Ab-1/ GM-Tg-cynog-IP1772-Ab-2;
GM-Tg-felg-IP1772-Ab-1/ GM-Tg-felg-IP1772-Ab-2; GM-Tg-cang-IP1772-Ab-1/ GM-Tg-cang-IP1772-Ab-2;
GM-Tg-bovg-IP1772-Ab-1/ GM-Tg-bovg-IP1772-Ab-2; GM-Tg-equg-IP1772-Ab-1/ GM-Tg-equg-IP1772-Ab-2
Products NameAnti-SMIM22 monoclonal antibody
Formatmab
Target NameSMIM22
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SMIM22 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1772-Ag-1Recombinant multi-species SIM22/ SMIM22/ CASIMO1 protein


    Target information

    Target IDGM-IP1772
    Target NameSMIM22
    Gene ID440335,432995,360478,106994933,102156841,105261317,102150140
    Gene Symbol and SynonymsCASIMO1,EG432995,Gm5480,RGD1563547,SMIM22
    Uniprot AccessionK7EJ46
    Uniprot Entry NameSIM22_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000267795
    Target ClassificationN/A

    The target: SMIM22, gene name: SMIM22, also named as CASIMO1. Involved in several processes, including lipid droplet formation; positive regulation of cell migration; and regulation of actin cytoskeleton organization. Predicted to be located in late endosome. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.