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Anti-SORCS1 monoclonal antibody
Pre-made anti-SORCS1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SORCS1/SORCS1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1787-Ab-1/ GM-Tg-hg-IP1787-Ab-2 | Anti-Human SORCS1 monoclonal antibody | Human |
| GM-Tg-rg-IP1787-Ab-1/ GM-Tg-rg-IP1787-Ab-2 | Anti-Rat SORCS1 monoclonal antibody | Rat |
| GM-Tg-mg-IP1787-Ab-1/ GM-Tg-mg-IP1787-Ab-2 | Anti-Mouse SORCS1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1787-Ab-1/ GM-Tg-cynog-IP1787-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SORCS1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1787-Ab-1/ GM-Tg-felg-IP1787-Ab-2 | Anti-Feline SORCS1 monoclonal antibody | Feline |
| GM-Tg-cang-IP1787-Ab-1/ GM-Tg-cang-IP1787-Ab-2 | Anti-Canine SORCS1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1787-Ab-1/ GM-Tg-bovg-IP1787-Ab-2 | Anti-Bovine SORCS1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1787-Ab-1/ GM-Tg-equg-IP1787-Ab-2 | Anti-Equine SORCS1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1787-Ab-1/ GM-Tg-hg-IP1787-Ab-2; GM-Tg-rg-IP1787-Ab-1/ GM-Tg-rg-IP1787-Ab-2; GM-Tg-mg-IP1787-Ab-1/ GM-Tg-mg-IP1787-Ab-2; GM-Tg-cynog-IP1787-Ab-1/ GM-Tg-cynog-IP1787-Ab-2; GM-Tg-felg-IP1787-Ab-1/ GM-Tg-felg-IP1787-Ab-2; GM-Tg-cang-IP1787-Ab-1/ GM-Tg-cang-IP1787-Ab-2; GM-Tg-bovg-IP1787-Ab-1/ GM-Tg-bovg-IP1787-Ab-2; GM-Tg-equg-IP1787-Ab-1/ GM-Tg-equg-IP1787-Ab-2 |
| Products Name | Anti-SORCS1 monoclonal antibody |
| Format | mab |
| Target Name | SORCS1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SORCS1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1787-Ag-1 | Recombinant multi-species SORC1/ SORCS1/ hSorCS protein |
Target information
| Target ID | GM-IP1787 |
| Target Name | SORCS1 |
| Gene ID | 114815,58178,309533,693969,477816,101097844,537536,100069383 |
| Gene Symbol and Synonyms | hSorCS,mSorCS,Sorcs,SORCS1 |
| Uniprot Accession | Q8WY21 |
| Uniprot Entry Name | SORC1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000108018 |
| Target Classification | N/A |
The target: SORCS1, gene name: SORCS1, also named as hSorCS. This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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