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Anti-SRSF3 monoclonal antibody
Pre-made anti-SRSF3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SRSF3/SRSF3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1820-Ab-1/ GM-Tg-hg-IP1820-Ab-2 | Anti-Human SRSF3 monoclonal antibody | Human |
| GM-Tg-rg-IP1820-Ab-1/ GM-Tg-rg-IP1820-Ab-2 | Anti-Rat SRSF3 monoclonal antibody | Rat |
| GM-Tg-mg-IP1820-Ab-1/ GM-Tg-mg-IP1820-Ab-2 | Anti-Mouse SRSF3 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1820-Ab-1/ GM-Tg-cynog-IP1820-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SRSF3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1820-Ab-1/ GM-Tg-felg-IP1820-Ab-2 | Anti-Feline SRSF3 monoclonal antibody | Feline |
| GM-Tg-cang-IP1820-Ab-1/ GM-Tg-cang-IP1820-Ab-2 | Anti-Canine SRSF3 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1820-Ab-1/ GM-Tg-bovg-IP1820-Ab-2 | Anti-Bovine SRSF3 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1820-Ab-1/ GM-Tg-equg-IP1820-Ab-2 | Anti-Equine SRSF3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1820-Ab-1/ GM-Tg-hg-IP1820-Ab-2; GM-Tg-rg-IP1820-Ab-1/ GM-Tg-rg-IP1820-Ab-2; GM-Tg-mg-IP1820-Ab-1/ GM-Tg-mg-IP1820-Ab-2; GM-Tg-cynog-IP1820-Ab-1/ GM-Tg-cynog-IP1820-Ab-2; GM-Tg-felg-IP1820-Ab-1/ GM-Tg-felg-IP1820-Ab-2; GM-Tg-cang-IP1820-Ab-1/ GM-Tg-cang-IP1820-Ab-2; GM-Tg-bovg-IP1820-Ab-1/ GM-Tg-bovg-IP1820-Ab-2; GM-Tg-equg-IP1820-Ab-1/ GM-Tg-equg-IP1820-Ab-2 |
| Products Name | Anti-SRSF3 monoclonal antibody |
| Format | mab |
| Target Name | SRSF3 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SRSF3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1820-Ag-1 | Recombinant multi-species SRSF3/ SFRS3/ SRp20 protein |
| ORF Viral Vector | vGMLP000996 | human SRSF3 Lentivirus particle |
| ORF Viral Vector | pGMLP000996 | human SRSF3 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000307 | mouse Srsf3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000307 | mouse Srsf3 Lentivirus particle |
Target information
| Target ID | GM-IP1820 |
| Target Name | SRSF3 |
| Gene ID | 6428,20383,361814,719123,403687,101081223,540276,100053744 |
| Gene Symbol and Synonyms | SFRS3,SRp20,SRSF3,X16 |
| Uniprot Accession | P84103,Q3SZR8 |
| Uniprot Entry Name | SRSF3_HUMAN,SRSF3_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000112081 |
| Target Classification | N/A |
The target: SRSF3, gene name: SRSF3, also named as SFRS3, SRp20. The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene. [provided by RefSeq, Sep 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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