Anti-SSR2 monoclonal antibody

Pre-made anti-SSR2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SSR2/SSR2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1825-Ab-1/ GM-Tg-hg-IP1825-Ab-2Anti-Human SSR2 monoclonal antibodyHuman
GM-Tg-rg-IP1825-Ab-1/ GM-Tg-rg-IP1825-Ab-2Anti-Rat SSR2 monoclonal antibodyRat
GM-Tg-mg-IP1825-Ab-1/ GM-Tg-mg-IP1825-Ab-2Anti-Mouse SSR2 monoclonal antibodyMouse
GM-Tg-cynog-IP1825-Ab-1/ GM-Tg-cynog-IP1825-Ab-2Anti-Cynomolgus/ Rhesus macaque SSR2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1825-Ab-1/ GM-Tg-felg-IP1825-Ab-2Anti-Feline SSR2 monoclonal antibodyFeline
GM-Tg-cang-IP1825-Ab-1/ GM-Tg-cang-IP1825-Ab-2Anti-Canine SSR2 monoclonal antibodyCanine
GM-Tg-bovg-IP1825-Ab-1/ GM-Tg-bovg-IP1825-Ab-2Anti-Bovine SSR2 monoclonal antibodyBovine
GM-Tg-equg-IP1825-Ab-1/ GM-Tg-equg-IP1825-Ab-2Anti-Equine SSR2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1825-Ab-1/ GM-Tg-hg-IP1825-Ab-2; GM-Tg-rg-IP1825-Ab-1/ GM-Tg-rg-IP1825-Ab-2;
GM-Tg-mg-IP1825-Ab-1/ GM-Tg-mg-IP1825-Ab-2; GM-Tg-cynog-IP1825-Ab-1/ GM-Tg-cynog-IP1825-Ab-2;
GM-Tg-felg-IP1825-Ab-1/ GM-Tg-felg-IP1825-Ab-2; GM-Tg-cang-IP1825-Ab-1/ GM-Tg-cang-IP1825-Ab-2;
GM-Tg-bovg-IP1825-Ab-1/ GM-Tg-bovg-IP1825-Ab-2; GM-Tg-equg-IP1825-Ab-1/ GM-Tg-equg-IP1825-Ab-2
Products NameAnti-SSR2 monoclonal antibody
Formatmab
Target NameSSR2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SSR2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1825-Ag-1Recombinant multi-species SSRB/ SSR2/ HSD25 protein


    Target information

    Target IDGM-IP1825
    Target NameSSR2
    Gene ID6746,66256,295235,719383,403950,101085095,506530,100063842
    Gene Symbol and Synonyms1500032E05Rik,gp25H,HSD25,SSR-beta,SSR2,TLAP,TRAP-BETA,TRAPB,TRAPbeta
    Uniprot AccessionP43308,P23438,Q5E9E4
    Uniprot Entry NameSSRB_HUMAN,SSRB_CANLF,SSRB_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000163479
    Target ClassificationN/A

    The target: SSR2, gene name: SSR2, also named as HSD25, TLAP, TRAP-BETA, TRAPB. The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.