Anti-ST3GAL6 monoclonal antibody
Pre-made anti-ST3GAL6 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP1828-Ab-1/ GM-Tg-hg-IP1828-Ab-2 | Anti-Human ST3GAL6 monoclonal antibody | Human |
GM-Tg-rg-IP1828-Ab-1/ GM-Tg-rg-IP1828-Ab-2 | Anti-Rat ST3GAL6 monoclonal antibody | Rat |
GM-Tg-mg-IP1828-Ab-1/ GM-Tg-mg-IP1828-Ab-2 | Anti-Mouse ST3GAL6 monoclonal antibody | Mouse |
GM-Tg-cynog-IP1828-Ab-1/ GM-Tg-cynog-IP1828-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ST3GAL6 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP1828-Ab-1/ GM-Tg-felg-IP1828-Ab-2 | Anti-Feline ST3GAL6 monoclonal antibody | Feline |
GM-Tg-cang-IP1828-Ab-1/ GM-Tg-cang-IP1828-Ab-2 | Anti-Canine ST3GAL6 monoclonal antibody | Canine |
GM-Tg-bovg-IP1828-Ab-1/ GM-Tg-bovg-IP1828-Ab-2 | Anti-Bovine ST3GAL6 monoclonal antibody | Bovine |
GM-Tg-equg-IP1828-Ab-1/ GM-Tg-equg-IP1828-Ab-2 | Anti-Equine ST3GAL6 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-IP1828-Ab-1/ GM-Tg-hg-IP1828-Ab-2; GM-Tg-rg-IP1828-Ab-1/ GM-Tg-rg-IP1828-Ab-2; GM-Tg-mg-IP1828-Ab-1/ GM-Tg-mg-IP1828-Ab-2; GM-Tg-cynog-IP1828-Ab-1/ GM-Tg-cynog-IP1828-Ab-2; GM-Tg-felg-IP1828-Ab-1/ GM-Tg-felg-IP1828-Ab-2; GM-Tg-cang-IP1828-Ab-1/ GM-Tg-cang-IP1828-Ab-2; GM-Tg-bovg-IP1828-Ab-1/ GM-Tg-bovg-IP1828-Ab-2; GM-Tg-equg-IP1828-Ab-1/ GM-Tg-equg-IP1828-Ab-2 |
Products Name | Anti-ST3GAL6 monoclonal antibody |
Format | mab |
Target Name | ST3GAL6 |
Protein Sub-location | Introcelluar Protein |
Category of antibody | |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-ST3GAL6 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-IP1828-Ag-1 | Recombinant multi-species SIA10/ ST3GAL6/ SIAT10 protein |
Target information
Target ID | GM-IP1828 |
Target Name | ST3GAL6 |
Gene ID | 10402,54613,304023,699096,478535,101091552,444860,100062218 |
Gene Symbol and Synonyms | 1700023B24Rik,SIAT10,ST3GAL6,ST3GALVI |
Uniprot Accession | Q9Y274,P61943,Q6H8M7 |
Uniprot Entry Name | SIA10_HUMAN,SIA10_RAT,SIA10_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000064225 |
Target Classification | N/A |
The target: ST3GAL6, gene name: ST3GAL6, also named as SIAT10, ST3GALVI. The protein encoded by this gene is a member of the sialyltransferase family. Members of this family are enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. [provided by RefSeq, Apr 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.