Anti-STT3A monoclonal antibody

Pre-made anti-STT3A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to STT3A/STT3A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1845-Ab-1/ GM-Tg-hg-IP1845-Ab-2Anti-Human STT3A monoclonal antibodyHuman
GM-Tg-rg-IP1845-Ab-1/ GM-Tg-rg-IP1845-Ab-2Anti-Rat STT3A monoclonal antibodyRat
GM-Tg-mg-IP1845-Ab-1/ GM-Tg-mg-IP1845-Ab-2Anti-Mouse STT3A monoclonal antibodyMouse
GM-Tg-cynog-IP1845-Ab-1/ GM-Tg-cynog-IP1845-Ab-2Anti-Cynomolgus/ Rhesus macaque STT3A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1845-Ab-1/ GM-Tg-felg-IP1845-Ab-2Anti-Feline STT3A monoclonal antibodyFeline
GM-Tg-cang-IP1845-Ab-1/ GM-Tg-cang-IP1845-Ab-2Anti-Canine STT3A monoclonal antibodyCanine
GM-Tg-bovg-IP1845-Ab-1/ GM-Tg-bovg-IP1845-Ab-2Anti-Bovine STT3A monoclonal antibodyBovine
GM-Tg-equg-IP1845-Ab-1/ GM-Tg-equg-IP1845-Ab-2Anti-Equine STT3A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1845-Ab-1/ GM-Tg-hg-IP1845-Ab-2; GM-Tg-rg-IP1845-Ab-1/ GM-Tg-rg-IP1845-Ab-2;
GM-Tg-mg-IP1845-Ab-1/ GM-Tg-mg-IP1845-Ab-2; GM-Tg-cynog-IP1845-Ab-1/ GM-Tg-cynog-IP1845-Ab-2;
GM-Tg-felg-IP1845-Ab-1/ GM-Tg-felg-IP1845-Ab-2; GM-Tg-cang-IP1845-Ab-1/ GM-Tg-cang-IP1845-Ab-2;
GM-Tg-bovg-IP1845-Ab-1/ GM-Tg-bovg-IP1845-Ab-2; GM-Tg-equg-IP1845-Ab-1/ GM-Tg-equg-IP1845-Ab-2
Products NameAnti-STT3A monoclonal antibody
Formatmab
Target NameSTT3A
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-STT3A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1845-Ag-1Recombinant multi-species STT3A/ I™1/ STT3-A protein


    Target information

    Target IDGM-IP1845
    Target NameSTT3A
    Gene ID3703,16430,500972,717056,489300,101083108,507815,100072333
    Gene Symbol and SynonymsB5,CDG1WAD,CDG1WAR,I™1,RGD1565793,STT3-A,STT3A,™C
    Uniprot AccessionP46977,F1PJP5,Q2KJI2
    Uniprot Entry NameSTT3A_HUMAN,STT3A_CANLF,STT3A_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseProstate Cancer
    Gene EnsemblENSG00000134910
    Target ClassificationN/A

    The target: STT3A, gene name: STT3A, also named as I™1, STT3-A, ™C. The protein encoded by this gene is a catalytic subunit of the N-oligosaccharyltransferase (OST) complex, which functions in the endoplasmic reticulum to transfer glycan chains to asparagine residues of target proteins. A separate complex containing a similar catalytic subunit with an overlapping function also exists. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.