Anti-SYNJ2BP monoclonal antibody

Pre-made anti-SYNJ2BP monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SYNJ2BP/SYNJ2BP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1870-Ab-1/ GM-Tg-hg-IP1870-Ab-2Anti-Human SYNJ2BP monoclonal antibodyHuman
GM-Tg-rg-IP1870-Ab-1/ GM-Tg-rg-IP1870-Ab-2Anti-Rat SYNJ2BP monoclonal antibodyRat
GM-Tg-mg-IP1870-Ab-1/ GM-Tg-mg-IP1870-Ab-2Anti-Mouse SYNJ2BP monoclonal antibodyMouse
GM-Tg-cynog-IP1870-Ab-1/ GM-Tg-cynog-IP1870-Ab-2Anti-Cynomolgus/ Rhesus macaque SYNJ2BP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1870-Ab-1/ GM-Tg-felg-IP1870-Ab-2Anti-Feline SYNJ2BP monoclonal antibodyFeline
GM-Tg-cang-IP1870-Ab-1/ GM-Tg-cang-IP1870-Ab-2Anti-Canine SYNJ2BP monoclonal antibodyCanine
GM-Tg-bovg-IP1870-Ab-1/ GM-Tg-bovg-IP1870-Ab-2Anti-Bovine SYNJ2BP monoclonal antibodyBovine
GM-Tg-equg-IP1870-Ab-1/ GM-Tg-equg-IP1870-Ab-2Anti-Equine SYNJ2BP monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1870-Ab-1/ GM-Tg-hg-IP1870-Ab-2; GM-Tg-rg-IP1870-Ab-1/ GM-Tg-rg-IP1870-Ab-2;
GM-Tg-mg-IP1870-Ab-1/ GM-Tg-mg-IP1870-Ab-2; GM-Tg-cynog-IP1870-Ab-1/ GM-Tg-cynog-IP1870-Ab-2;
GM-Tg-felg-IP1870-Ab-1/ GM-Tg-felg-IP1870-Ab-2; GM-Tg-cang-IP1870-Ab-1/ GM-Tg-cang-IP1870-Ab-2;
GM-Tg-bovg-IP1870-Ab-1/ GM-Tg-bovg-IP1870-Ab-2; GM-Tg-equg-IP1870-Ab-1/ GM-Tg-equg-IP1870-Ab-2
Products NameAnti-SYNJ2BP monoclonal antibody
Formatmab
Target NameSYNJ2BP
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SYNJ2BP monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1870-Ag-1Recombinant multi-species SYJ2B/ SYNJ2BP/ ARIP2 protein


    Target information

    Target IDGM-IP1870
    Target NameSYNJ2BP
    Gene ID55333,24071,64531,713312,490757,101081641,525107,100049833
    Gene Symbol and SynonymsActRIP4,ARIP2,D12Wsu118e,OMP25,SYNJ2BP
    Uniprot AccessionP57105,Q9WVJ4,Q3T0C9
    Uniprot Entry NameSYJ2B_HUMAN,SYJ2B_RAT,SYJ2B_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000213463
    Target ClassificationN/A

    The target: SYNJ2BP, gene name: SYNJ2BP, also named as ARIP2, OMP25. Predicted to enable type II activin receptor binding activity. Involved in several processes, including negative regulation of endothelial cell migration; negative regulation of sprouting angiogenesis; and regulation of signal transduction. Located in mitochondrion. Is integral component of mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.