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Anti-TAP2 monoclonal antibody
Pre-made anti-TAP2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to TAP2/TAP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1881-Ab-1/ GM-Tg-hg-IP1881-Ab-2 | Anti-Human TAP2 monoclonal antibody | Human |
| GM-Tg-rg-IP1881-Ab-1/ GM-Tg-rg-IP1881-Ab-2 | Anti-Rat TAP2 monoclonal antibody | Rat |
| GM-Tg-mg-IP1881-Ab-1/ GM-Tg-mg-IP1881-Ab-2 | Anti-Mouse TAP2 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1881-Ab-1/ GM-Tg-cynog-IP1881-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TAP2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1881-Ab-1/ GM-Tg-felg-IP1881-Ab-2 | Anti-Feline TAP2 monoclonal antibody | Feline |
| GM-Tg-cang-IP1881-Ab-1/ GM-Tg-cang-IP1881-Ab-2 | Anti-Canine TAP2 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1881-Ab-1/ GM-Tg-bovg-IP1881-Ab-2 | Anti-Bovine TAP2 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1881-Ab-1/ GM-Tg-equg-IP1881-Ab-2 | Anti-Equine TAP2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1881-Ab-1/ GM-Tg-hg-IP1881-Ab-2; GM-Tg-rg-IP1881-Ab-1/ GM-Tg-rg-IP1881-Ab-2; GM-Tg-mg-IP1881-Ab-1/ GM-Tg-mg-IP1881-Ab-2; GM-Tg-cynog-IP1881-Ab-1/ GM-Tg-cynog-IP1881-Ab-2; GM-Tg-felg-IP1881-Ab-1/ GM-Tg-felg-IP1881-Ab-2; GM-Tg-cang-IP1881-Ab-1/ GM-Tg-cang-IP1881-Ab-2; GM-Tg-bovg-IP1881-Ab-1/ GM-Tg-bovg-IP1881-Ab-2; GM-Tg-equg-IP1881-Ab-1/ GM-Tg-equg-IP1881-Ab-2 |
| Products Name | Anti-TAP2 monoclonal antibody |
| Format | mab |
| Target Name | TAP2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TAP2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1881-Ag-1 | Recombinant multi-species TAP2/ ABC18/ ABCB3 protein |
Target information
| Target ID | GM-IP1881 |
| Target Name | TAP2 |
| Gene ID | 6891,21355,24812,717742,474864,101089770,100052423 |
| Gene Symbol and Synonyms | ABC18,ABCB3,APT2,Cim,D6S217E,Ham-2,Ham2,jas,MTP2,PSF-2,PSF2,RING11,Tap-2,TAP2,Y1 |
| Uniprot Accession | Q03519,P36372 |
| Uniprot Entry Name | TAP2_HUMAN,TAP2_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000204267 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: TAP2, gene name: TAP2, also named as ABC18, ABCB3, APT2, D6S217E, PSF-2, PSF2, RING11. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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