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Anti-TAPT1 monoclonal antibody
Pre-made anti-TAPT1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to TAPT1/TAPT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1883-Ab-1/ GM-Tg-hg-IP1883-Ab-2 | Anti-Human TAPT1 monoclonal antibody | Human |
| GM-Tg-rg-IP1883-Ab-1/ GM-Tg-rg-IP1883-Ab-2 | Anti-Rat TAPT1 monoclonal antibody | Rat |
| GM-Tg-mg-IP1883-Ab-1/ GM-Tg-mg-IP1883-Ab-2 | Anti-Mouse TAPT1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1883-Ab-1/ GM-Tg-cynog-IP1883-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TAPT1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1883-Ab-1/ GM-Tg-felg-IP1883-Ab-2 | Anti-Feline TAPT1 monoclonal antibody | Feline |
| GM-Tg-cang-IP1883-Ab-1/ GM-Tg-cang-IP1883-Ab-2 | Anti-Canine TAPT1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1883-Ab-1/ GM-Tg-bovg-IP1883-Ab-2 | Anti-Bovine TAPT1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1883-Ab-1/ GM-Tg-equg-IP1883-Ab-2 | Anti-Equine TAPT1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1883-Ab-1/ GM-Tg-hg-IP1883-Ab-2; GM-Tg-rg-IP1883-Ab-1/ GM-Tg-rg-IP1883-Ab-2; GM-Tg-mg-IP1883-Ab-1/ GM-Tg-mg-IP1883-Ab-2; GM-Tg-cynog-IP1883-Ab-1/ GM-Tg-cynog-IP1883-Ab-2; GM-Tg-felg-IP1883-Ab-1/ GM-Tg-felg-IP1883-Ab-2; GM-Tg-cang-IP1883-Ab-1/ GM-Tg-cang-IP1883-Ab-2; GM-Tg-bovg-IP1883-Ab-1/ GM-Tg-bovg-IP1883-Ab-2; GM-Tg-equg-IP1883-Ab-1/ GM-Tg-equg-IP1883-Ab-2 |
| Products Name | Anti-TAPT1 monoclonal antibody |
| Format | mab |
| Target Name | TAPT1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TAPT1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1883-Ag-1 | Recombinant multi-species TAPT1/ CMVFR/ OCLSBG protein |
Target information
| Target ID | GM-IP1883 |
| Target Name | TAPT1 |
| Gene ID | 202018,231225,305386,714712,488815,101081135,615598,100068801 |
| Gene Symbol and Synonyms | 4932414K18Rik,CMVFR,OCLSBG,RGD1309656,TAPT1 |
| Uniprot Accession | Q6NXT6 |
| Uniprot Entry Name | TAPT1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000169762 |
| Target Classification | N/A |
The target: TAPT1, gene name: TAPT1, also named as CMVFR, OCLSBG. This gene encodes a highly conserved protein that localizes to the centrosome and/or ciliary basal body. Mutations in this gene disrupt Golgi morphology and trafficking and normal primary cilium formation and these mutations are congenitally manifested by severe undermineralization of the intra-uterine skeleton. A mutation in the mouse ortholog of this gene results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. In mouse, this gene is thought to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development. [provided by RefSeq, Jan 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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