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Anti-TBC1D20 monoclonal antibody
Pre-made anti-TBC1D20 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to TBC1D20/TBC1D20 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1888-Ab-1/ GM-Tg-hg-IP1888-Ab-2 | Anti-Human TBC1D20 monoclonal antibody | Human |
| GM-Tg-rg-IP1888-Ab-1/ GM-Tg-rg-IP1888-Ab-2 | Anti-Rat TBC1D20 monoclonal antibody | Rat |
| GM-Tg-mg-IP1888-Ab-1/ GM-Tg-mg-IP1888-Ab-2 | Anti-Mouse TBC1D20 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1888-Ab-1/ GM-Tg-cynog-IP1888-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TBC1D20 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1888-Ab-1/ GM-Tg-felg-IP1888-Ab-2 | Anti-Feline TBC1D20 monoclonal antibody | Feline |
| GM-Tg-cang-IP1888-Ab-1/ GM-Tg-cang-IP1888-Ab-2 | Anti-Canine TBC1D20 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1888-Ab-1/ GM-Tg-bovg-IP1888-Ab-2 | Anti-Bovine TBC1D20 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1888-Ab-1/ GM-Tg-equg-IP1888-Ab-2 | Anti-Equine TBC1D20 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1888-Ab-1/ GM-Tg-hg-IP1888-Ab-2; GM-Tg-rg-IP1888-Ab-1/ GM-Tg-rg-IP1888-Ab-2; GM-Tg-mg-IP1888-Ab-1/ GM-Tg-mg-IP1888-Ab-2; GM-Tg-cynog-IP1888-Ab-1/ GM-Tg-cynog-IP1888-Ab-2; GM-Tg-felg-IP1888-Ab-1/ GM-Tg-felg-IP1888-Ab-2; GM-Tg-cang-IP1888-Ab-1/ GM-Tg-cang-IP1888-Ab-2; GM-Tg-bovg-IP1888-Ab-1/ GM-Tg-bovg-IP1888-Ab-2; GM-Tg-equg-IP1888-Ab-1/ GM-Tg-equg-IP1888-Ab-2 |
| Products Name | Anti-TBC1D20 monoclonal antibody |
| Format | mab |
| Target Name | TBC1D20 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TBC1D20 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1888-Ag-1 | Recombinant multi-species TBC20/ TBC1D20/ C20orf140 protein |
| ORF Viral Vector | pGMLPm004969 | mouse Tbc1d20 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004969 | mouse Tbc1d20 Lentivirus particle |
Target information
| Target ID | GM-IP1888 |
| Target Name | TBC1D20 |
| Gene ID | 128637,67231,362237,716852,485817,101083925,504543,102151098 |
| Gene Symbol and Synonyms | 1110028I04Rik,2810442O16Rik,bs,C20orf140,TBC1D20,WARBM4 |
| Uniprot Accession | Q96BZ9,Q2T9Q1 |
| Uniprot Entry Name | TBC20_HUMAN,TBC20_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000125875 |
| Target Classification | N/A |
The target: TBC1D20, gene name: TBC1D20, also named as C20orf140, WARBM4. This gene encodes a protein that belongs to a family of GTPase activator proteins of Rab-like small GTPases. The encoded protein and its cognate GTPase, Rab1, bind the nonstructural protein 5A (NS5A) of the hepatitis C virus (HCV) to mediate viral replication. Depletion of this protein inhibits replication of the virus and HCV infection. Mutations in this gene are associated with Warburg micro syndrome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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