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Anti-TBC1D7 monoclonal antibody
Pre-made anti-TBC1D7 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to TBC1D7/TBC1D7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1894-Ab-1/ GM-Tg-hg-IP1894-Ab-2 | Anti-Human TBC1D7 monoclonal antibody | Human |
| GM-Tg-rg-IP1894-Ab-1/ GM-Tg-rg-IP1894-Ab-2 | Anti-Rat TBC1D7 monoclonal antibody | Rat |
| GM-Tg-mg-IP1894-Ab-1/ GM-Tg-mg-IP1894-Ab-2 | Anti-Mouse TBC1D7 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1894-Ab-1/ GM-Tg-cynog-IP1894-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TBC1D7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1894-Ab-1/ GM-Tg-felg-IP1894-Ab-2 | Anti-Feline TBC1D7 monoclonal antibody | Feline |
| GM-Tg-cang-IP1894-Ab-1/ GM-Tg-cang-IP1894-Ab-2 | Anti-Canine TBC1D7 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1894-Ab-1/ GM-Tg-bovg-IP1894-Ab-2 | Anti-Bovine TBC1D7 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1894-Ab-1/ GM-Tg-equg-IP1894-Ab-2 | Anti-Equine TBC1D7 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1894-Ab-1/ GM-Tg-hg-IP1894-Ab-2; GM-Tg-rg-IP1894-Ab-1/ GM-Tg-rg-IP1894-Ab-2; GM-Tg-mg-IP1894-Ab-1/ GM-Tg-mg-IP1894-Ab-2; GM-Tg-cynog-IP1894-Ab-1/ GM-Tg-cynog-IP1894-Ab-2; GM-Tg-felg-IP1894-Ab-1/ GM-Tg-felg-IP1894-Ab-2; GM-Tg-cang-IP1894-Ab-1/ GM-Tg-cang-IP1894-Ab-2; GM-Tg-bovg-IP1894-Ab-1/ GM-Tg-bovg-IP1894-Ab-2; GM-Tg-equg-IP1894-Ab-1/ GM-Tg-equg-IP1894-Ab-2 |
| Products Name | Anti-TBC1D7 monoclonal antibody |
| Format | mab |
| Target Name | TBC1D7 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TBC1D7 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1894-Ag-1 | Recombinant multi-species TBCD7/ TBC1D7/ MGCPH protein |
Target information
| Target ID | GM-IP1894 |
| Target Name | TBC1D7 |
| Gene ID | 51256,67046,361227,706015,532704,100051625 |
| Gene Symbol and Synonyms | 2610009C09Rik,MGCPH,PIG51,TBC1D7,TBC7 |
| Uniprot Accession | Q9P0N9,Q5E9C4 |
| Uniprot Entry Name | TBCD7_HUMAN,TBCD7_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000145979 |
| Target Classification | N/A |
The target: TBC1D7, gene name: TBC1D7, also named as MGCPH, PIG51, TBC7. This gene encodes a member of the TBC-domain containing protein family. The encoded protein functions as a subunit of the tuberous sclerosis TSC1-TSC2 complex which plays a role in the regulation of cellular growth and differentiation. Mutations in this gene have been associated with autosomal recessive megalencephaly. Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between this locus and downstream LOC100130357. [provided by RefSeq, Jan 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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