Anti-TECR monoclonal antibody

Pre-made anti-TECR monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TECR/TECR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1900-Ab-1/ GM-Tg-hg-IP1900-Ab-2Anti-Human TECR monoclonal antibodyHuman
GM-Tg-rg-IP1900-Ab-1/ GM-Tg-rg-IP1900-Ab-2Anti-Rat TECR monoclonal antibodyRat
GM-Tg-mg-IP1900-Ab-1/ GM-Tg-mg-IP1900-Ab-2Anti-Mouse TECR monoclonal antibodyMouse
GM-Tg-cynog-IP1900-Ab-1/ GM-Tg-cynog-IP1900-Ab-2Anti-Cynomolgus/ Rhesus macaque TECR monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1900-Ab-1/ GM-Tg-felg-IP1900-Ab-2Anti-Feline TECR monoclonal antibodyFeline
GM-Tg-cang-IP1900-Ab-1/ GM-Tg-cang-IP1900-Ab-2Anti-Canine TECR monoclonal antibodyCanine
GM-Tg-bovg-IP1900-Ab-1/ GM-Tg-bovg-IP1900-Ab-2Anti-Bovine TECR monoclonal antibodyBovine
GM-Tg-equg-IP1900-Ab-1/ GM-Tg-equg-IP1900-Ab-2Anti-Equine TECR monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1900-Ab-1/ GM-Tg-hg-IP1900-Ab-2; GM-Tg-rg-IP1900-Ab-1/ GM-Tg-rg-IP1900-Ab-2;
GM-Tg-mg-IP1900-Ab-1/ GM-Tg-mg-IP1900-Ab-2; GM-Tg-cynog-IP1900-Ab-1/ GM-Tg-cynog-IP1900-Ab-2;
GM-Tg-felg-IP1900-Ab-1/ GM-Tg-felg-IP1900-Ab-2; GM-Tg-cang-IP1900-Ab-1/ GM-Tg-cang-IP1900-Ab-2;
GM-Tg-bovg-IP1900-Ab-1/ GM-Tg-bovg-IP1900-Ab-2; GM-Tg-equg-IP1900-Ab-1/ GM-Tg-equg-IP1900-Ab-2
Products NameAnti-TECR monoclonal antibody
Formatmab
Target NameTECR
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TECR monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1900-Ag-1Recombinant multi-species TECR/ GPSN2/ MRT14 protein


    Target information

    Target IDGM-IP1900
    Target NameTECR
    Gene ID9524,106529,191576,718928,476687,101091601,614105,100065024
    Gene Symbol and Synonyms2410016D23Rik,A230102P12Rik,D17Ertd178e,GPSN2,MRT14,SC2,TECR,TER
    Uniprot AccessionQ9NZ01,Q64232,Q3ZCD7
    Uniprot Entry NameTECR_HUMAN,TECR_RAT,TECR_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000099797
    Target ClassificationN/A

    The target: TECR, gene name: TECR, also named as GPSN2, MRT14, SC2, TER. This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.