Anti-TIMM21 monoclonal antibody

Pre-made anti-TIMM21 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TIMM21/TIMM21 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1915-Ab-1/ GM-Tg-hg-IP1915-Ab-2Anti-Human TIMM21 monoclonal antibodyHuman
GM-Tg-rg-IP1915-Ab-1/ GM-Tg-rg-IP1915-Ab-2Anti-Rat TIMM21 monoclonal antibodyRat
GM-Tg-mg-IP1915-Ab-1/ GM-Tg-mg-IP1915-Ab-2Anti-Mouse TIMM21 monoclonal antibodyMouse
GM-Tg-cynog-IP1915-Ab-1/ GM-Tg-cynog-IP1915-Ab-2Anti-Cynomolgus/ Rhesus macaque TIMM21 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1915-Ab-1/ GM-Tg-felg-IP1915-Ab-2Anti-Feline TIMM21 monoclonal antibodyFeline
GM-Tg-cang-IP1915-Ab-1/ GM-Tg-cang-IP1915-Ab-2Anti-Canine TIMM21 monoclonal antibodyCanine
GM-Tg-bovg-IP1915-Ab-1/ GM-Tg-bovg-IP1915-Ab-2Anti-Bovine TIMM21 monoclonal antibodyBovine
GM-Tg-equg-IP1915-Ab-1/ GM-Tg-equg-IP1915-Ab-2Anti-Equine TIMM21 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1915-Ab-1/ GM-Tg-hg-IP1915-Ab-2; GM-Tg-rg-IP1915-Ab-1/ GM-Tg-rg-IP1915-Ab-2;
GM-Tg-mg-IP1915-Ab-1/ GM-Tg-mg-IP1915-Ab-2; GM-Tg-cynog-IP1915-Ab-1/ GM-Tg-cynog-IP1915-Ab-2;
GM-Tg-felg-IP1915-Ab-1/ GM-Tg-felg-IP1915-Ab-2; GM-Tg-cang-IP1915-Ab-1/ GM-Tg-cang-IP1915-Ab-2;
GM-Tg-bovg-IP1915-Ab-1/ GM-Tg-bovg-IP1915-Ab-2; GM-Tg-equg-IP1915-Ab-1/ GM-Tg-equg-IP1915-Ab-2
Products NameAnti-TIMM21 monoclonal antibody
Formatmab
Target NameTIMM21
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TIMM21 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1915-Ag-1Recombinant multi-species TIM21/ TIMM21/ C18orf55 protein


    Target information

    Target IDGM-IP1915
    Target NameTIMM21
    Gene ID29090,67105,307210,694581,476170,101095524,614633,100052148
    Gene Symbol and Synonyms1700034H14Rik,2700002I20Rik,C17H18orf55,C18H18orf55,C18orf55,C1H18orf55,C24H18orf55,HSPC154,RGD1307279,TIM21,TIMM21
    Uniprot AccessionQ9BVV7,Q5U2X7,Q3SZV6
    Uniprot Entry NameTIM21_HUMAN,TIM21_RAT,TIM21_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000075336
    Target ClassificationN/A

    The target: TIMM21, gene name: TIMM21, also named as C18orf55, HSPC154, TIM21. Involved in mitochondrial cytochrome c oxidase assembly; mitochondrial respiratory chain complex I assembly; and protein import into mitochondrial matrix. Part of TIM23 mitochondrial import inner membrane translocase complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.