Anti-™2D2 monoclonal antibody

Pre-made anti-™2D2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™2D2/™2D2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1920-Ab-1/ GM-Tg-hg-IP1920-Ab-2Anti-Human ™2D2 monoclonal antibodyHuman
GM-Tg-rg-IP1920-Ab-1/ GM-Tg-rg-IP1920-Ab-2Anti-Rat ™2D2 monoclonal antibodyRat
GM-Tg-mg-IP1920-Ab-1/ GM-Tg-mg-IP1920-Ab-2Anti-Mouse ™2D2 monoclonal antibodyMouse
GM-Tg-cynog-IP1920-Ab-1/ GM-Tg-cynog-IP1920-Ab-2Anti-Cynomolgus/ Rhesus macaque ™2D2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1920-Ab-1/ GM-Tg-felg-IP1920-Ab-2Anti-Feline ™2D2 monoclonal antibodyFeline
GM-Tg-cang-IP1920-Ab-1/ GM-Tg-cang-IP1920-Ab-2Anti-Canine ™2D2 monoclonal antibodyCanine
GM-Tg-bovg-IP1920-Ab-1/ GM-Tg-bovg-IP1920-Ab-2Anti-Bovine ™2D2 monoclonal antibodyBovine
GM-Tg-equg-IP1920-Ab-1/ GM-Tg-equg-IP1920-Ab-2Anti-Equine ™2D2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1920-Ab-1/ GM-Tg-hg-IP1920-Ab-2; GM-Tg-rg-IP1920-Ab-1/ GM-Tg-rg-IP1920-Ab-2;
GM-Tg-mg-IP1920-Ab-1/ GM-Tg-mg-IP1920-Ab-2; GM-Tg-cynog-IP1920-Ab-1/ GM-Tg-cynog-IP1920-Ab-2;
GM-Tg-felg-IP1920-Ab-1/ GM-Tg-felg-IP1920-Ab-2; GM-Tg-cang-IP1920-Ab-1/ GM-Tg-cang-IP1920-Ab-2;
GM-Tg-bovg-IP1920-Ab-1/ GM-Tg-bovg-IP1920-Ab-2; GM-Tg-equg-IP1920-Ab-1/ GM-Tg-equg-IP1920-Ab-2
Products NameAnti-™2D2 monoclonal antibody
Formatmab
Target Name™2D2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™2D2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1920-Ag-1Recombinant multi-species ™2D2/ BLP1 protein


    Target information

    Target IDGM-IP1920
    Target Name™2D2
    Gene ID83877,69742,290833,701007,482850,101085118,507906,100058661
    Gene Symbol and Synonyms2410018G23Rik,BLP1,RGD1306769,™2D2
    Uniprot AccessionQ9BX73,Q566R2,Q2TA35
    Uniprot Entry Name™2D2_HUMAN,™2D2_RAT,™2D2_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000169490
    Target ClassificationN/A

    The target: ™2D2, gene name: ™2D2, also named as BLP1. The protein encoded by this gene contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily. This protein has sequence and structural similarities to the beta-amyloid binding protein (BBP), but, unlike BBP, it does not regulate a response to beta-amyloid peptide. This protein may have regulatory roles in cell death or proliferation signal cascades. This gene has multiple alternatively spliced transcript variants which encode two different isoforms. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.