Anti-™2D3 monoclonal antibody

Pre-made anti-™2D3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™2D3/™2D3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1921-Ab-1/ GM-Tg-hg-IP1921-Ab-2Anti-Human ™2D3 monoclonal antibodyHuman
GM-Tg-rg-IP1921-Ab-1/ GM-Tg-rg-IP1921-Ab-2Anti-Rat ™2D3 monoclonal antibodyRat
GM-Tg-mg-IP1921-Ab-1/ GM-Tg-mg-IP1921-Ab-2Anti-Mouse ™2D3 monoclonal antibodyMouse
GM-Tg-cynog-IP1921-Ab-1/ GM-Tg-cynog-IP1921-Ab-2Anti-Cynomolgus/ Rhesus macaque ™2D3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1921-Ab-1/ GM-Tg-felg-IP1921-Ab-2Anti-Feline ™2D3 monoclonal antibodyFeline
GM-Tg-cang-IP1921-Ab-1/ GM-Tg-cang-IP1921-Ab-2Anti-Canine ™2D3 monoclonal antibodyCanine
GM-Tg-bovg-IP1921-Ab-1/ GM-Tg-bovg-IP1921-Ab-2Anti-Bovine ™2D3 monoclonal antibodyBovine
GM-Tg-equg-IP1921-Ab-1/ GM-Tg-equg-IP1921-Ab-2Anti-Equine ™2D3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1921-Ab-1/ GM-Tg-hg-IP1921-Ab-2; GM-Tg-rg-IP1921-Ab-1/ GM-Tg-rg-IP1921-Ab-2;
GM-Tg-mg-IP1921-Ab-1/ GM-Tg-mg-IP1921-Ab-2; GM-Tg-cynog-IP1921-Ab-1/ GM-Tg-cynog-IP1921-Ab-2;
GM-Tg-felg-IP1921-Ab-1/ GM-Tg-felg-IP1921-Ab-2; GM-Tg-cang-IP1921-Ab-1/ GM-Tg-cang-IP1921-Ab-2;
GM-Tg-bovg-IP1921-Ab-1/ GM-Tg-bovg-IP1921-Ab-2; GM-Tg-equg-IP1921-Ab-1/ GM-Tg-equg-IP1921-Ab-2
Products NameAnti-™2D3 monoclonal antibody
Formatmab
Target Name™2D3
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™2D3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1921-Ag-1Recombinant multi-species ™2D3/ BLP2 protein


    Target information

    Target IDGM-IP1921
    Target Name™2D3
    Gene ID80213,68634,292995,695111,479020,101081550,512588,100057905
    Gene Symbol and Synonyms1110025I09Rik,5930422O05Rik,BLP2,RGD1564929,™2D3
    Uniprot AccessionQ9BRN9
    Uniprot Entry Name™2D3_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000184277
    Target ClassificationN/A

    The target: ™2D3, gene name: ™2D3, also named as BLP2. The protein encoded by this gene contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily. This protein has sequence and structural similarities to the beta-amyloid binding protein (BBP), but, unlike BBP, it does not regulate a response to beta-amyloid peptide. This protein may have regulatory roles in cell death or proliferation signal cascades. Several alternatively spliced transcript variants of this gene are described but the full length nature of some variants has not been determined. Multiple polyadenylation sites have been found in this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.