Anti-™4SF19 monoclonal antibody

Pre-made anti-™4SF19 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™4SF19/™4SF19 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1924-Ab-1/ GM-Tg-hg-IP1924-Ab-2Anti-Human ™4SF19 monoclonal antibodyHuman
GM-Tg-rg-IP1924-Ab-1/ GM-Tg-rg-IP1924-Ab-2Anti-Rat ™4SF19 monoclonal antibodyRat
GM-Tg-mg-IP1924-Ab-1/ GM-Tg-mg-IP1924-Ab-2Anti-Mouse ™4SF19 monoclonal antibodyMouse
GM-Tg-cynog-IP1924-Ab-1/ GM-Tg-cynog-IP1924-Ab-2Anti-Cynomolgus/ Rhesus macaque ™4SF19 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1924-Ab-1/ GM-Tg-felg-IP1924-Ab-2Anti-Feline ™4SF19 monoclonal antibodyFeline
GM-Tg-cang-IP1924-Ab-1/ GM-Tg-cang-IP1924-Ab-2Anti-Canine ™4SF19 monoclonal antibodyCanine
GM-Tg-bovg-IP1924-Ab-1/ GM-Tg-bovg-IP1924-Ab-2Anti-Bovine ™4SF19 monoclonal antibodyBovine
GM-Tg-equg-IP1924-Ab-1/ GM-Tg-equg-IP1924-Ab-2Anti-Equine ™4SF19 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1924-Ab-1/ GM-Tg-hg-IP1924-Ab-2; GM-Tg-rg-IP1924-Ab-1/ GM-Tg-rg-IP1924-Ab-2;
GM-Tg-mg-IP1924-Ab-1/ GM-Tg-mg-IP1924-Ab-2; GM-Tg-cynog-IP1924-Ab-1/ GM-Tg-cynog-IP1924-Ab-2;
GM-Tg-felg-IP1924-Ab-1/ GM-Tg-felg-IP1924-Ab-2; GM-Tg-cang-IP1924-Ab-1/ GM-Tg-cang-IP1924-Ab-2;
GM-Tg-bovg-IP1924-Ab-1/ GM-Tg-bovg-IP1924-Ab-2; GM-Tg-equg-IP1924-Ab-1/ GM-Tg-equg-IP1924-Ab-2
Products NameAnti-™4SF19 monoclonal antibody
Formatmab
Target Name™4SF19
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™4SF19 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1924-Ag-1Recombinant multi-species T4S19/ ™4SF19/ OC™4 protein


    Target information

    Target IDGM-IP1924
    Target Name™4SF19
    Gene ID116211,277203,288044,711179,101100076,101906348,100069913
    Gene Symbol and SynonymsEG277203,OC™4,RGD1560486,™4SF19
    Uniprot AccessionQ96DZ7
    Uniprot Entry NameT4S19_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000145107
    Target ClassificationN/A

    The target: ™4SF19, gene name: ™4SF19, also named as OC™4. The protein encoded by this gene is a member of the four-transmembrane L6 superfamily. Members of this family function in various cellular processes including cell proliferation, motility, and adhesion via their interactions with integrins. In human brain tissue, this gene is expressed at high levels in the parietal lobe, occipital lobe, hippocampus, pons, white matter, corpus callosum, and cerebellum. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.