Anti-™4SF4 monoclonal antibody

Pre-made anti-™4SF4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™4SF4/™4SF4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1925-Ab-1/ GM-Tg-hg-IP1925-Ab-2Anti-Human ™4SF4 monoclonal antibodyHuman
GM-Tg-rg-IP1925-Ab-1/ GM-Tg-rg-IP1925-Ab-2Anti-Rat ™4SF4 monoclonal antibodyRat
GM-Tg-mg-IP1925-Ab-1/ GM-Tg-mg-IP1925-Ab-2Anti-Mouse ™4SF4 monoclonal antibodyMouse
GM-Tg-cynog-IP1925-Ab-1/ GM-Tg-cynog-IP1925-Ab-2Anti-Cynomolgus/ Rhesus macaque ™4SF4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1925-Ab-1/ GM-Tg-felg-IP1925-Ab-2Anti-Feline ™4SF4 monoclonal antibodyFeline
GM-Tg-cang-IP1925-Ab-1/ GM-Tg-cang-IP1925-Ab-2Anti-Canine ™4SF4 monoclonal antibodyCanine
GM-Tg-bovg-IP1925-Ab-1/ GM-Tg-bovg-IP1925-Ab-2Anti-Bovine ™4SF4 monoclonal antibodyBovine
GM-Tg-equg-IP1925-Ab-1/ GM-Tg-equg-IP1925-Ab-2Anti-Equine ™4SF4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1925-Ab-1/ GM-Tg-hg-IP1925-Ab-2; GM-Tg-rg-IP1925-Ab-1/ GM-Tg-rg-IP1925-Ab-2;
GM-Tg-mg-IP1925-Ab-1/ GM-Tg-mg-IP1925-Ab-2; GM-Tg-cynog-IP1925-Ab-1/ GM-Tg-cynog-IP1925-Ab-2;
GM-Tg-felg-IP1925-Ab-1/ GM-Tg-felg-IP1925-Ab-2; GM-Tg-cang-IP1925-Ab-1/ GM-Tg-cang-IP1925-Ab-2;
GM-Tg-bovg-IP1925-Ab-1/ GM-Tg-bovg-IP1925-Ab-2; GM-Tg-equg-IP1925-Ab-1/ GM-Tg-equg-IP1925-Ab-2
Products NameAnti-™4SF4 monoclonal antibody
Formatmab
Target Name™4SF4
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™4SF4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1925-Ag-1Recombinant multi-species T4S4/ ™4SF4/ IL™P protein


    Target information

    Target IDGM-IP1925
    Target Name™4SF4
    Gene ID7104,229302,116467,711653,611654,101100661,507646,100058318
    Gene Symbol and Synonymsil-™P,IL™P,Lrtm4,™4SF4
    Uniprot AccessionP48230,Q9EQL5
    Uniprot Entry NameT4S4_HUMAN,T4S4_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000169903
    Target ClassificationN/A

    The target: ™4SF4, gene name: ™4SF4, also named as IL™P, il-™P. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that can regulate cell proliferation.[provided by RefSeq, Mar 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.