Anti-™EM107 monoclonal antibody

Pre-made anti-™EM107 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™EM107/™EM107 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1958-Ab-1/ GM-Tg-hg-IP1958-Ab-2Anti-Human ™EM107 monoclonal antibodyHuman
GM-Tg-rg-IP1958-Ab-1/ GM-Tg-rg-IP1958-Ab-2Anti-Rat ™EM107 monoclonal antibodyRat
GM-Tg-mg-IP1958-Ab-1/ GM-Tg-mg-IP1958-Ab-2Anti-Mouse ™EM107 monoclonal antibodyMouse
GM-Tg-cynog-IP1958-Ab-1/ GM-Tg-cynog-IP1958-Ab-2Anti-Cynomolgus/ Rhesus macaque ™EM107 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1958-Ab-1/ GM-Tg-felg-IP1958-Ab-2Anti-Feline ™EM107 monoclonal antibodyFeline
GM-Tg-cang-IP1958-Ab-1/ GM-Tg-cang-IP1958-Ab-2Anti-Canine ™EM107 monoclonal antibodyCanine
GM-Tg-bovg-IP1958-Ab-1/ GM-Tg-bovg-IP1958-Ab-2Anti-Bovine ™EM107 monoclonal antibodyBovine
GM-Tg-equg-IP1958-Ab-1/ GM-Tg-equg-IP1958-Ab-2Anti-Equine ™EM107 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1958-Ab-1/ GM-Tg-hg-IP1958-Ab-2; GM-Tg-rg-IP1958-Ab-1/ GM-Tg-rg-IP1958-Ab-2;
GM-Tg-mg-IP1958-Ab-1/ GM-Tg-mg-IP1958-Ab-2; GM-Tg-cynog-IP1958-Ab-1/ GM-Tg-cynog-IP1958-Ab-2;
GM-Tg-felg-IP1958-Ab-1/ GM-Tg-felg-IP1958-Ab-2; GM-Tg-cang-IP1958-Ab-1/ GM-Tg-cang-IP1958-Ab-2;
GM-Tg-bovg-IP1958-Ab-1/ GM-Tg-bovg-IP1958-Ab-2; GM-Tg-equg-IP1958-Ab-1/ GM-Tg-equg-IP1958-Ab-2
Products NameAnti-™EM107 monoclonal antibody
Formatmab
Target Name™EM107
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™EM107 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1958-Ag-1Recombinant multi-species ™107/ ™EM107/ GRVS638 protein


    Target information

    Target IDGM-IP1958
    Target Name™EM107
    Gene ID84314,66910,691750,716961,119881480,101080838,509812,100062420
    Gene Symbol and Synonyms1110004B13Rik,2810049P21Rik,GRVS638,JBTS29,MKS13,PRO1268,™EM107
    Uniprot AccessionQ6UX40,D3ZFW5
    Uniprot Entry Name™107_HUMAN,™107_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000179029
    Target ClassificationN/A

    The target: ™EM107, gene name: ™EM107, also named as GRVS638, JBTS29, MKS13, PRO1268. This gene encodes a transmembrane protein and component of the primary cilia transition zone. The encoded protein regulates ciliogenesis and ciliary protein composition. Human fibroblasts expressing a mutant allele of this gene exhibit reduced numbers of cilia, altered cilia length, and impaired sonic hedgehog signaling. In human patients, different mutations in this gene cause different ciliopathies, including Meckel-Gruber syndrome and orofaciodigital syndrome. [provided by RefSeq, May 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.