Anti-™EM132E monoclonal antibody

Pre-made anti-™EM132E monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™EM132E/™EM132E products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1978-Ab-1/ GM-Tg-hg-IP1978-Ab-2Anti-Human ™EM132E monoclonal antibodyHuman
GM-Tg-rg-IP1978-Ab-1/ GM-Tg-rg-IP1978-Ab-2Anti-Rat ™EM132E monoclonal antibodyRat
GM-Tg-mg-IP1978-Ab-1/ GM-Tg-mg-IP1978-Ab-2Anti-Mouse ™EM132E monoclonal antibodyMouse
GM-Tg-cynog-IP1978-Ab-1/ GM-Tg-cynog-IP1978-Ab-2Anti-Cynomolgus/ Rhesus macaque ™EM132E monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1978-Ab-1/ GM-Tg-felg-IP1978-Ab-2Anti-Feline ™EM132E monoclonal antibodyFeline
GM-Tg-cang-IP1978-Ab-1/ GM-Tg-cang-IP1978-Ab-2Anti-Canine ™EM132E monoclonal antibodyCanine
GM-Tg-bovg-IP1978-Ab-1/ GM-Tg-bovg-IP1978-Ab-2Anti-Bovine ™EM132E monoclonal antibodyBovine
GM-Tg-equg-IP1978-Ab-1/ GM-Tg-equg-IP1978-Ab-2Anti-Equine ™EM132E monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1978-Ab-1/ GM-Tg-hg-IP1978-Ab-2; GM-Tg-rg-IP1978-Ab-1/ GM-Tg-rg-IP1978-Ab-2;
GM-Tg-mg-IP1978-Ab-1/ GM-Tg-mg-IP1978-Ab-2; GM-Tg-cynog-IP1978-Ab-1/ GM-Tg-cynog-IP1978-Ab-2;
GM-Tg-felg-IP1978-Ab-1/ GM-Tg-felg-IP1978-Ab-2; GM-Tg-cang-IP1978-Ab-1/ GM-Tg-cang-IP1978-Ab-2;
GM-Tg-bovg-IP1978-Ab-1/ GM-Tg-bovg-IP1978-Ab-2; GM-Tg-equg-IP1978-Ab-1/ GM-Tg-equg-IP1978-Ab-2
Products NameAnti-™EM132E monoclonal antibody
Formatmab
Target Name™EM132E
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™EM132E monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1978-Ag-1Recombinant multi-species T132E/ ™EM132E/ DFNB99 protein


    Target information

    Target IDGM-IP1978
    Target Name™EM132E
    Gene ID124842,270893,287564,715004,491147,101100261,506723,100071685
    Gene Symbol and SynonymsDFNB99,Gm644,RGD1565522,™EM132E
    Uniprot AccessionQ6IEE7
    Uniprot Entry NameT132E_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000181291
    Target ClassificationN/A

    The target: ™EM132E, gene name: ™EM132E, also named as DFNB99. Involved in posterior lateral line neuromast hair cell development. Predicted to be located in cell body. Implicated in autosomal recessive nonsyndromic deafness 99. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.