Anti-™EM138 monoclonal antibody

Pre-made anti-™EM138 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™EM138/™EM138 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1982-Ab-1/ GM-Tg-hg-IP1982-Ab-2Anti-Human ™EM138 monoclonal antibodyHuman
GM-Tg-rg-IP1982-Ab-1/ GM-Tg-rg-IP1982-Ab-2Anti-Rat ™EM138 monoclonal antibodyRat
GM-Tg-mg-IP1982-Ab-1/ GM-Tg-mg-IP1982-Ab-2Anti-Mouse ™EM138 monoclonal antibodyMouse
GM-Tg-cynog-IP1982-Ab-1/ GM-Tg-cynog-IP1982-Ab-2Anti-Cynomolgus/ Rhesus macaque ™EM138 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1982-Ab-1/ GM-Tg-felg-IP1982-Ab-2Anti-Feline ™EM138 monoclonal antibodyFeline
GM-Tg-cang-IP1982-Ab-1/ GM-Tg-cang-IP1982-Ab-2Anti-Canine ™EM138 monoclonal antibodyCanine
GM-Tg-bovg-IP1982-Ab-1/ GM-Tg-bovg-IP1982-Ab-2Anti-Bovine ™EM138 monoclonal antibodyBovine
GM-Tg-equg-IP1982-Ab-1/ GM-Tg-equg-IP1982-Ab-2Anti-Equine ™EM138 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1982-Ab-1/ GM-Tg-hg-IP1982-Ab-2; GM-Tg-rg-IP1982-Ab-1/ GM-Tg-rg-IP1982-Ab-2;
GM-Tg-mg-IP1982-Ab-1/ GM-Tg-mg-IP1982-Ab-2; GM-Tg-cynog-IP1982-Ab-1/ GM-Tg-cynog-IP1982-Ab-2;
GM-Tg-felg-IP1982-Ab-1/ GM-Tg-felg-IP1982-Ab-2; GM-Tg-cang-IP1982-Ab-1/ GM-Tg-cang-IP1982-Ab-2;
GM-Tg-bovg-IP1982-Ab-1/ GM-Tg-bovg-IP1982-Ab-2; GM-Tg-equg-IP1982-Ab-1/ GM-Tg-equg-IP1982-Ab-2
Products NameAnti-™EM138 monoclonal antibody
Formatmab
Target Name™EM138
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™EM138 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1982-Ag-1Recombinant multi-species ™138/ ™EM138/ HSPC196 protein


    Target information

    Target IDGM-IP1982
    Target Name™EM138
    Gene ID51524,72982,361728,693905,612314,101081575,514277,100059706
    Gene Symbol and Synonyms1700113I01Rik,2900055D14Rik,HSPC196,™EM138
    Uniprot AccessionQ9NPI0,B1WBM3,A5PJY4
    Uniprot Entry Name™138_HUMAN,™138_RAT,™138_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000149483
    Target ClassificationN/A

    The target: ™EM138, gene name: ™EM138, also named as HSPC196. This gene encodes a multi-pass transmembrane protein. Reduced expression of this gene in mouse fibroblasts causes short cilia and failure of ciliogenesis. Expression of this gene is tightly coordinated with expression of the neighboring gene ™EM216. Mutations in this gene are associated with the autosomal recessive neurodevelopmental disorder Joubert Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.