Anti-™EM176B monoclonal antibody

Pre-made anti-™EM176B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™EM176B/™EM176B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2015-Ab-1/ GM-Tg-hg-IP2015-Ab-2Anti-Human ™EM176B monoclonal antibodyHuman
GM-Tg-rg-IP2015-Ab-1/ GM-Tg-rg-IP2015-Ab-2Anti-Rat ™EM176B monoclonal antibodyRat
GM-Tg-mg-IP2015-Ab-1/ GM-Tg-mg-IP2015-Ab-2Anti-Mouse ™EM176B monoclonal antibodyMouse
GM-Tg-cynog-IP2015-Ab-1/ GM-Tg-cynog-IP2015-Ab-2Anti-Cynomolgus/ Rhesus macaque ™EM176B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2015-Ab-1/ GM-Tg-felg-IP2015-Ab-2Anti-Feline ™EM176B monoclonal antibodyFeline
GM-Tg-cang-IP2015-Ab-1/ GM-Tg-cang-IP2015-Ab-2Anti-Canine ™EM176B monoclonal antibodyCanine
GM-Tg-bovg-IP2015-Ab-1/ GM-Tg-bovg-IP2015-Ab-2Anti-Bovine ™EM176B monoclonal antibodyBovine
GM-Tg-equg-IP2015-Ab-1/ GM-Tg-equg-IP2015-Ab-2Anti-Equine ™EM176B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2015-Ab-1/ GM-Tg-hg-IP2015-Ab-2; GM-Tg-rg-IP2015-Ab-1/ GM-Tg-rg-IP2015-Ab-2;
GM-Tg-mg-IP2015-Ab-1/ GM-Tg-mg-IP2015-Ab-2; GM-Tg-cynog-IP2015-Ab-1/ GM-Tg-cynog-IP2015-Ab-2;
GM-Tg-felg-IP2015-Ab-1/ GM-Tg-felg-IP2015-Ab-2; GM-Tg-cang-IP2015-Ab-1/ GM-Tg-cang-IP2015-Ab-2;
GM-Tg-bovg-IP2015-Ab-1/ GM-Tg-bovg-IP2015-Ab-2; GM-Tg-equg-IP2015-Ab-1/ GM-Tg-equg-IP2015-Ab-2
Products NameAnti-™EM176B monoclonal antibody
Formatmab
Target Name™EM176B
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™EM176B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2015-Ag-1Recombinant multi-species T176B/ ™EM176B/ LR8 protein


    Target information

    Target IDGM-IP2015
    Target Name™EM176B
    Gene ID28959,65963,171411,713997,610914,101095812,615505,100063299
    Gene Symbol and Synonyms1810009M01Rik,Clast1,LR8,MS4B2,™EM176B,Torid
    Uniprot AccessionQ3YBM2,Q925D4
    Uniprot Entry NameT176B_HUMAN,T176B_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000106565
    Target ClassificationN/A

    The target: ™EM176B, gene name: ™EM176B, also named as LR8, MS4B2. Predicted to be involved in negative regulation of dendritic cell differentiation. Predicted to be located in nuclear membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.