Anti-™EM225 monoclonal antibody

Pre-made anti-™EM225 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™EM225/™EM225 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2057-Ab-1/ GM-Tg-hg-IP2057-Ab-2Anti-Human ™EM225 monoclonal antibodyHuman
GM-Tg-rg-IP2057-Ab-1/ GM-Tg-rg-IP2057-Ab-2Anti-Rat ™EM225 monoclonal antibodyRat
GM-Tg-mg-IP2057-Ab-1/ GM-Tg-mg-IP2057-Ab-2Anti-Mouse ™EM225 monoclonal antibodyMouse
GM-Tg-cynog-IP2057-Ab-1/ GM-Tg-cynog-IP2057-Ab-2Anti-Cynomolgus/ Rhesus macaque ™EM225 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2057-Ab-1/ GM-Tg-felg-IP2057-Ab-2Anti-Feline ™EM225 monoclonal antibodyFeline
GM-Tg-cang-IP2057-Ab-1/ GM-Tg-cang-IP2057-Ab-2Anti-Canine ™EM225 monoclonal antibodyCanine
GM-Tg-bovg-IP2057-Ab-1/ GM-Tg-bovg-IP2057-Ab-2Anti-Bovine ™EM225 monoclonal antibodyBovine
GM-Tg-equg-IP2057-Ab-1/ GM-Tg-equg-IP2057-Ab-2Anti-Equine ™EM225 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2057-Ab-1/ GM-Tg-hg-IP2057-Ab-2; GM-Tg-rg-IP2057-Ab-1/ GM-Tg-rg-IP2057-Ab-2;
GM-Tg-mg-IP2057-Ab-1/ GM-Tg-mg-IP2057-Ab-2; GM-Tg-cynog-IP2057-Ab-1/ GM-Tg-cynog-IP2057-Ab-2;
GM-Tg-felg-IP2057-Ab-1/ GM-Tg-felg-IP2057-Ab-2; GM-Tg-cang-IP2057-Ab-1/ GM-Tg-cang-IP2057-Ab-2;
GM-Tg-bovg-IP2057-Ab-1/ GM-Tg-bovg-IP2057-Ab-2; GM-Tg-equg-IP2057-Ab-1/ GM-Tg-equg-IP2057-Ab-2
Products NameAnti-™EM225 monoclonal antibody
Formatmab
Target Name™EM225
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™EM225 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2057-Ag-1Recombinant multi-species ™225/ ™EM225/ PMP22CD protein


    Target information

    Target IDGM-IP2057
    Target Name™EM225
    Gene ID338661,75667,500980,709207,610179,101093543,519985,100071779
    Gene Symbol and Synonyms1700030E15Rik,PMP22CD,PPP1R154,SPATA47,™EM225,Tnen225
    Uniprot AccessionQ6GV28,Q6GV27,Q32KQ5
    Uniprot Entry Name™225_HUMAN,™225_RAT,™225_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000204300
    Target ClassificationN/A

    The target: ™EM225, gene name: ™EM225, also named as PMP22CD, PPP1R154, SPATA47. Predicted to be involved in negative regulation of phosphatase activity. Predicted to be located in acrosomal membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.