Anti-™EM33 monoclonal antibody

Pre-made anti-™EM33 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™EM33/™EM33 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2094-Ab-1/ GM-Tg-hg-IP2094-Ab-2Anti-Human ™EM33 monoclonal antibodyHuman
GM-Tg-rg-IP2094-Ab-1/ GM-Tg-rg-IP2094-Ab-2Anti-Rat ™EM33 monoclonal antibodyRat
GM-Tg-mg-IP2094-Ab-1/ GM-Tg-mg-IP2094-Ab-2Anti-Mouse ™EM33 monoclonal antibodyMouse
GM-Tg-cynog-IP2094-Ab-1/ GM-Tg-cynog-IP2094-Ab-2Anti-Cynomolgus/ Rhesus macaque ™EM33 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2094-Ab-1/ GM-Tg-felg-IP2094-Ab-2Anti-Feline ™EM33 monoclonal antibodyFeline
GM-Tg-cang-IP2094-Ab-1/ GM-Tg-cang-IP2094-Ab-2Anti-Canine ™EM33 monoclonal antibodyCanine
GM-Tg-bovg-IP2094-Ab-1/ GM-Tg-bovg-IP2094-Ab-2Anti-Bovine ™EM33 monoclonal antibodyBovine
GM-Tg-equg-IP2094-Ab-1/ GM-Tg-equg-IP2094-Ab-2Anti-Equine ™EM33 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2094-Ab-1/ GM-Tg-hg-IP2094-Ab-2; GM-Tg-rg-IP2094-Ab-1/ GM-Tg-rg-IP2094-Ab-2;
GM-Tg-mg-IP2094-Ab-1/ GM-Tg-mg-IP2094-Ab-2; GM-Tg-cynog-IP2094-Ab-1/ GM-Tg-cynog-IP2094-Ab-2;
GM-Tg-felg-IP2094-Ab-1/ GM-Tg-felg-IP2094-Ab-2; GM-Tg-cang-IP2094-Ab-1/ GM-Tg-cang-IP2094-Ab-2;
GM-Tg-bovg-IP2094-Ab-1/ GM-Tg-bovg-IP2094-Ab-2; GM-Tg-equg-IP2094-Ab-1/ GM-Tg-equg-IP2094-Ab-2
Products NameAnti-™EM33 monoclonal antibody
Formatmab
Target Name™EM33
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™EM33 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2094-Ag-1Recombinant multi-species ™M33/ ™EM33/ 1600019D15Rik protein


    Target information

    Target IDGM-IP2094
    Target Name™EM33
    Gene ID55161,67878,59303,702063,612937,101092851,614879,100054802
    Gene Symbol and Synonyms1110006G02Rik,1600019D15Rik,2410089A21Rik,2700052H22Rik,5430406L04Rik,db83,Pom33,SHINC-3,SHINC3,™EM33
    Uniprot AccessionP57088,Q9Z142
    Uniprot Entry Name™M33_HUMAN,™M33_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000109133
    Target ClassificationN/A

    The target: ™EM33, gene name: ™EM33, also named as 1600019D15Rik, SHINC-3, SHINC3. Involved in positive regulation of endoplasmic reticulum unfolded protein response; regulation of endoplasmic reticulum tubular network organization; and response to endoplasmic reticulum stress. Located in endoplasmic reticulum membrane; melanosome; and nuclear envelope. Is integral component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.