Anti-™EM67 monoclonal antibody

Pre-made anti-™EM67 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™EM67/™EM67 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2120-Ab-1/ GM-Tg-hg-IP2120-Ab-2Anti-Human ™EM67 monoclonal antibodyHuman
GM-Tg-rg-IP2120-Ab-1/ GM-Tg-rg-IP2120-Ab-2Anti-Rat ™EM67 monoclonal antibodyRat
GM-Tg-mg-IP2120-Ab-1/ GM-Tg-mg-IP2120-Ab-2Anti-Mouse ™EM67 monoclonal antibodyMouse
GM-Tg-cynog-IP2120-Ab-1/ GM-Tg-cynog-IP2120-Ab-2Anti-Cynomolgus/ Rhesus macaque ™EM67 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2120-Ab-1/ GM-Tg-felg-IP2120-Ab-2Anti-Feline ™EM67 monoclonal antibodyFeline
GM-Tg-cang-IP2120-Ab-1/ GM-Tg-cang-IP2120-Ab-2Anti-Canine ™EM67 monoclonal antibodyCanine
GM-Tg-bovg-IP2120-Ab-1/ GM-Tg-bovg-IP2120-Ab-2Anti-Bovine ™EM67 monoclonal antibodyBovine
GM-Tg-equg-IP2120-Ab-1/ GM-Tg-equg-IP2120-Ab-2Anti-Equine ™EM67 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2120-Ab-1/ GM-Tg-hg-IP2120-Ab-2; GM-Tg-rg-IP2120-Ab-1/ GM-Tg-rg-IP2120-Ab-2;
GM-Tg-mg-IP2120-Ab-1/ GM-Tg-mg-IP2120-Ab-2; GM-Tg-cynog-IP2120-Ab-1/ GM-Tg-cynog-IP2120-Ab-2;
GM-Tg-felg-IP2120-Ab-1/ GM-Tg-felg-IP2120-Ab-2; GM-Tg-cang-IP2120-Ab-1/ GM-Tg-cang-IP2120-Ab-2;
GM-Tg-bovg-IP2120-Ab-1/ GM-Tg-bovg-IP2120-Ab-2; GM-Tg-equg-IP2120-Ab-1/ GM-Tg-equg-IP2120-Ab-2
Products NameAnti-™EM67 monoclonal antibody
Formatmab
Target Name™EM67
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™EM67 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2120-Ag-1Recombinant multi-species MKS3/ ™EM67/ JBTS6 protein


    Target information

    Target IDGM-IP2120
    Target Name™EM67
    Gene ID91147,329795,313067,698631,487049,101089077,506762,100051660
    Gene Symbol and Synonyms5330408M12Rik,B230117O07,b2b1163.1Clo,b2b1291.1Clo,JBTS6,MECKELIN,MKS3,NPHP11,™EM67,TNEM67,Wpk
    Uniprot AccessionQ5HYA8,P0C152
    Uniprot Entry NameMKS3_HUMAN,MKS3_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000164953
    Target ClassificationN/A

    The target: ™EM67, gene name: ™EM67, also named as JBTS6, MECKELIN, MKS3, NPHP11, TNEM67. The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6). [provided by RefSeq, Nov 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.