Anti-™PRSS9 monoclonal antibody

Pre-made anti-™PRSS9 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™PRSS9/™PRSS9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2148-Ab-1/ GM-Tg-hg-IP2148-Ab-2Anti-Human ™PRSS9 monoclonal antibodyHuman
GM-Tg-rg-IP2148-Ab-1/ GM-Tg-rg-IP2148-Ab-2Anti-Rat ™PRSS9 monoclonal antibodyRat
GM-Tg-mg-IP2148-Ab-1/ GM-Tg-mg-IP2148-Ab-2Anti-Mouse ™PRSS9 monoclonal antibodyMouse
GM-Tg-cynog-IP2148-Ab-1/ GM-Tg-cynog-IP2148-Ab-2Anti-Cynomolgus/ Rhesus macaque ™PRSS9 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2148-Ab-1/ GM-Tg-felg-IP2148-Ab-2Anti-Feline ™PRSS9 monoclonal antibodyFeline
GM-Tg-cang-IP2148-Ab-1/ GM-Tg-cang-IP2148-Ab-2Anti-Canine ™PRSS9 monoclonal antibodyCanine
GM-Tg-bovg-IP2148-Ab-1/ GM-Tg-bovg-IP2148-Ab-2Anti-Bovine ™PRSS9 monoclonal antibodyBovine
GM-Tg-equg-IP2148-Ab-1/ GM-Tg-equg-IP2148-Ab-2Anti-Equine ™PRSS9 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2148-Ab-1/ GM-Tg-hg-IP2148-Ab-2; GM-Tg-rg-IP2148-Ab-1/ GM-Tg-rg-IP2148-Ab-2;
GM-Tg-mg-IP2148-Ab-1/ GM-Tg-mg-IP2148-Ab-2; GM-Tg-cynog-IP2148-Ab-1/ GM-Tg-cynog-IP2148-Ab-2;
GM-Tg-felg-IP2148-Ab-1/ GM-Tg-felg-IP2148-Ab-2; GM-Tg-cang-IP2148-Ab-1/ GM-Tg-cang-IP2148-Ab-2;
GM-Tg-bovg-IP2148-Ab-1/ GM-Tg-bovg-IP2148-Ab-2; GM-Tg-equg-IP2148-Ab-1/ GM-Tg-equg-IP2148-Ab-2
Products NameAnti-™PRSS9 monoclonal antibody
Formatmab
Target Name™PRSS9
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™PRSS9 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2148-Ag-1Recombinant multi-species ™PS9/ ™PRSS9 protein


    Target information

    Target IDGM-IP2148
    Target Name™PRSS9
    Gene ID360200,432478,314636,721489,612163,101081523,518647,100146332
    Gene Symbol and SynonymsSerase-1B,™PRSS9
    Uniprot AccessionQ7Z410,P69526
    Uniprot Entry Name™PS9_HUMAN,™PS9_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000178297
    Target ClassificationN/A

    The target: ™PRSS9, gene name: ™PRSS9, also named as . The protein encoded by this gene is a membrane-bound type II serine polyprotease that is cleaved to release three different proteases. Two of the proteases are active and can be inhibited by serine protease inhibitors, and one is thought to be catalytically inactive. This gene enhances the invasive capability of pancreatic cancer cells and may be involved in cancer progression. [provided by RefSeq, Jul 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.