Anti-™TC4 monoclonal antibody

Pre-made anti-™TC4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™TC4/™TC4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2152-Ab-1/ GM-Tg-hg-IP2152-Ab-2Anti-Human ™TC4 monoclonal antibodyHuman
GM-Tg-rg-IP2152-Ab-1/ GM-Tg-rg-IP2152-Ab-2Anti-Rat ™TC4 monoclonal antibodyRat
GM-Tg-mg-IP2152-Ab-1/ GM-Tg-mg-IP2152-Ab-2Anti-Mouse ™TC4 monoclonal antibodyMouse
GM-Tg-cynog-IP2152-Ab-1/ GM-Tg-cynog-IP2152-Ab-2Anti-Cynomolgus/ Rhesus macaque ™TC4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2152-Ab-1/ GM-Tg-felg-IP2152-Ab-2Anti-Feline ™TC4 monoclonal antibodyFeline
GM-Tg-cang-IP2152-Ab-1/ GM-Tg-cang-IP2152-Ab-2Anti-Canine ™TC4 monoclonal antibodyCanine
GM-Tg-bovg-IP2152-Ab-1/ GM-Tg-bovg-IP2152-Ab-2Anti-Bovine ™TC4 monoclonal antibodyBovine
GM-Tg-equg-IP2152-Ab-1/ GM-Tg-equg-IP2152-Ab-2Anti-Equine ™TC4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2152-Ab-1/ GM-Tg-hg-IP2152-Ab-2; GM-Tg-rg-IP2152-Ab-1/ GM-Tg-rg-IP2152-Ab-2;
GM-Tg-mg-IP2152-Ab-1/ GM-Tg-mg-IP2152-Ab-2; GM-Tg-cynog-IP2152-Ab-1/ GM-Tg-cynog-IP2152-Ab-2;
GM-Tg-felg-IP2152-Ab-1/ GM-Tg-felg-IP2152-Ab-2; GM-Tg-cang-IP2152-Ab-1/ GM-Tg-cang-IP2152-Ab-2;
GM-Tg-bovg-IP2152-Ab-1/ GM-Tg-bovg-IP2152-Ab-2; GM-Tg-equg-IP2152-Ab-1/ GM-Tg-equg-IP2152-Ab-2
Products NameAnti-™TC4 monoclonal antibody
Formatmab
Target Name™TC4
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™TC4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2152-Ag-1Recombinant multi-species ™TC4 protein


    Target information

    Target IDGM-IP2152
    Target Name™TC4
    Gene ID84899,70551,290501,706341,100855496,101081355,539972,100062494
    Gene Symbol and Synonyms4930403J22Rik,5730419O14Rik,RGD1560183,™TC4
    Uniprot AccessionQ5T4D3
    Uniprot Entry Name™TC4_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000125247
    Target ClassificationN/A

    The target: ™TC4, gene name: ™TC4, also named as . This gene encodes a transmembrane protein that belongs to family of proteins containing an N-terminal transmembrane domain and a C-terminal tetratricopeptide repeat (TPR) domain. TPR domains mediate protein-protein interactions in various cellular processes, such as synaptic vesicle fusion, protein folding, and protein translocation. A pseudogene of this gene has been defined on chromosome 5. [provided by RefSeq, Apr 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.