Anti-™X4 monoclonal antibody

Pre-made anti-™X4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™X4/™X4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2156-Ab-1/ GM-Tg-hg-IP2156-Ab-2Anti-Human ™X4 monoclonal antibodyHuman
GM-Tg-rg-IP2156-Ab-1/ GM-Tg-rg-IP2156-Ab-2Anti-Rat ™X4 monoclonal antibodyRat
GM-Tg-mg-IP2156-Ab-1/ GM-Tg-mg-IP2156-Ab-2Anti-Mouse ™X4 monoclonal antibodyMouse
GM-Tg-cynog-IP2156-Ab-1/ GM-Tg-cynog-IP2156-Ab-2Anti-Cynomolgus/ Rhesus macaque ™X4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2156-Ab-1/ GM-Tg-felg-IP2156-Ab-2Anti-Feline ™X4 monoclonal antibodyFeline
GM-Tg-cang-IP2156-Ab-1/ GM-Tg-cang-IP2156-Ab-2Anti-Canine ™X4 monoclonal antibodyCanine
GM-Tg-bovg-IP2156-Ab-1/ GM-Tg-bovg-IP2156-Ab-2Anti-Bovine ™X4 monoclonal antibodyBovine
GM-Tg-equg-IP2156-Ab-1/ GM-Tg-equg-IP2156-Ab-2Anti-Equine ™X4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2156-Ab-1/ GM-Tg-hg-IP2156-Ab-2; GM-Tg-rg-IP2156-Ab-1/ GM-Tg-rg-IP2156-Ab-2;
GM-Tg-mg-IP2156-Ab-1/ GM-Tg-mg-IP2156-Ab-2; GM-Tg-cynog-IP2156-Ab-1/ GM-Tg-cynog-IP2156-Ab-2;
GM-Tg-felg-IP2156-Ab-1/ GM-Tg-felg-IP2156-Ab-2; GM-Tg-cang-IP2156-Ab-1/ GM-Tg-cang-IP2156-Ab-2;
GM-Tg-bovg-IP2156-Ab-1/ GM-Tg-bovg-IP2156-Ab-2; GM-Tg-equg-IP2156-Ab-1/ GM-Tg-equg-IP2156-Ab-2
Products NameAnti-™X4 monoclonal antibody
Formatmab
Target Name™X4
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™X4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2156-Ag-1Recombinant multi-species ™X4/ DJ971N18.2/ PDIA14 protein


    Target information

    Target IDGM-IP2156
    Target Name™X4
    Gene ID56255,52837,296182,718375,477161,101092020,618015,100065101
    Gene Symbol and Synonyms2810417D04Rik,4930500L08Rik,D2Bwg1356e,DJ971N18.2,mKIAA1162,PDIA14,RGD1305146,™X4,TXNDC13
    Uniprot AccessionQ9H1E5
    Uniprot Entry Name™X4_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000125827
    Target ClassificationN/A

    The target: ™X4, gene name: ™X4, also named as DJ971N18.2, PDIA14, TXNDC13. This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and C-terminal ASP/GLU-rich calcium binding domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The encoded protein has been shown to have reductase activity in vitro. [provided by RefSeq, Jan 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.