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Anti-TNMD monoclonal antibody
Pre-made anti-TNMD monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to TNMD/TNMD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2157-Ab-1/ GM-Tg-hg-IP2157-Ab-2 | Anti-Human TNMD monoclonal antibody | Human |
| GM-Tg-rg-IP2157-Ab-1/ GM-Tg-rg-IP2157-Ab-2 | Anti-Rat TNMD monoclonal antibody | Rat |
| GM-Tg-mg-IP2157-Ab-1/ GM-Tg-mg-IP2157-Ab-2 | Anti-Mouse TNMD monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2157-Ab-1/ GM-Tg-cynog-IP2157-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TNMD monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2157-Ab-1/ GM-Tg-felg-IP2157-Ab-2 | Anti-Feline TNMD monoclonal antibody | Feline |
| GM-Tg-cang-IP2157-Ab-1/ GM-Tg-cang-IP2157-Ab-2 | Anti-Canine TNMD monoclonal antibody | Canine |
| GM-Tg-bovg-IP2157-Ab-1/ GM-Tg-bovg-IP2157-Ab-2 | Anti-Bovine TNMD monoclonal antibody | Bovine |
| GM-Tg-equg-IP2157-Ab-1/ GM-Tg-equg-IP2157-Ab-2 | Anti-Equine TNMD monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2157-Ab-1/ GM-Tg-hg-IP2157-Ab-2; GM-Tg-rg-IP2157-Ab-1/ GM-Tg-rg-IP2157-Ab-2; GM-Tg-mg-IP2157-Ab-1/ GM-Tg-mg-IP2157-Ab-2; GM-Tg-cynog-IP2157-Ab-1/ GM-Tg-cynog-IP2157-Ab-2; GM-Tg-felg-IP2157-Ab-1/ GM-Tg-felg-IP2157-Ab-2; GM-Tg-cang-IP2157-Ab-1/ GM-Tg-cang-IP2157-Ab-2; GM-Tg-bovg-IP2157-Ab-1/ GM-Tg-bovg-IP2157-Ab-2; GM-Tg-equg-IP2157-Ab-1/ GM-Tg-equg-IP2157-Ab-2 |
| Products Name | Anti-TNMD monoclonal antibody |
| Format | mab |
| Target Name | TNMD |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TNMD monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2157-Ag-1 | Recombinant multi-species TNMD/ BRICD4/ CHM1L protein |
Target information
| Target ID | GM-IP2157 |
| Target Name | TNMD |
| Gene ID | 64102,64103,64104,700526,119868217,101085104,781292,100033840 |
| Gene Symbol and Synonyms | 1110017I01Rik,BRICD4,CHM1L,TEM,TNMD |
| Uniprot Accession | Q9H2S6,Q9ESC2 |
| Uniprot Entry Name | TNMD_HUMAN,TNMD_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000000005 |
| Target Classification | N/A |
The target: TNMD, gene name: TNMD, also named as BRICD4, CHM1L, TEM. This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated. [provided by RefSeq, Sep 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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