Anti-TOMM70 monoclonal antibody

Pre-made anti-TOMM70 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TOMM70/TOMM70 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2161-Ab-1/ GM-Tg-hg-IP2161-Ab-2Anti-Human TOMM70 monoclonal antibodyHuman
GM-Tg-rg-IP2161-Ab-1/ GM-Tg-rg-IP2161-Ab-2Anti-Rat TOMM70 monoclonal antibodyRat
GM-Tg-mg-IP2161-Ab-1/ GM-Tg-mg-IP2161-Ab-2Anti-Mouse TOMM70 monoclonal antibodyMouse
GM-Tg-cynog-IP2161-Ab-1/ GM-Tg-cynog-IP2161-Ab-2Anti-Cynomolgus/ Rhesus macaque TOMM70 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2161-Ab-1/ GM-Tg-felg-IP2161-Ab-2Anti-Feline TOMM70 monoclonal antibodyFeline
GM-Tg-cang-IP2161-Ab-1/ GM-Tg-cang-IP2161-Ab-2Anti-Canine TOMM70 monoclonal antibodyCanine
GM-Tg-bovg-IP2161-Ab-1/ GM-Tg-bovg-IP2161-Ab-2Anti-Bovine TOMM70 monoclonal antibodyBovine
GM-Tg-equg-IP2161-Ab-1/ GM-Tg-equg-IP2161-Ab-2Anti-Equine TOMM70 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2161-Ab-1/ GM-Tg-hg-IP2161-Ab-2; GM-Tg-rg-IP2161-Ab-1/ GM-Tg-rg-IP2161-Ab-2;
GM-Tg-mg-IP2161-Ab-1/ GM-Tg-mg-IP2161-Ab-2; GM-Tg-cynog-IP2161-Ab-1/ GM-Tg-cynog-IP2161-Ab-2;
GM-Tg-felg-IP2161-Ab-1/ GM-Tg-felg-IP2161-Ab-2; GM-Tg-cang-IP2161-Ab-1/ GM-Tg-cang-IP2161-Ab-2;
GM-Tg-bovg-IP2161-Ab-1/ GM-Tg-bovg-IP2161-Ab-2; GM-Tg-equg-IP2161-Ab-1/ GM-Tg-equg-IP2161-Ab-2
Products NameAnti-TOMM70 monoclonal antibody
Formatmab
Target NameTOMM70
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TOMM70 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2161-Ag-1Recombinant multi-species TOM70/ TOMM70/ TOMM70A protein


    Target information

    Target IDGM-IP2161
    Target NameTOMM70
    Gene ID9868,28185,304017,700347,478541,101093292,507707,100072274
    Gene Symbol and Synonyms2610044B22Rik,D16Ium22,D16Ium22e,D16Wsu109e,mKIAA0719,Tom70,TOMM70,TOMM70A
    Uniprot AccessionO94826,Q75Q39
    Uniprot Entry NameTOM70_HUMAN,TOM70_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000154174
    Target ClassificationN/A

    The target: TOMM70, gene name: TOMM70, also named as TOMM70A, Tom70. This gene encodes an import receptor of the outer mitochondrial membrane that is part of the translocase of the outer membrane complex. This protein is involved in the import of mitochondrial precursor proteins. The protein interacts with the SARS-CoV and SARS-Cov-2 ORF9b proteins. [provided by RefSeq, Dec 2021].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.