Anti-TOR1AIP1 monoclonal antibody

Pre-made anti-TOR1AIP1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TOR1AIP1/TOR1AIP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2163-Ab-1/ GM-Tg-hg-IP2163-Ab-2Anti-Human TOR1AIP1 monoclonal antibodyHuman
GM-Tg-rg-IP2163-Ab-1/ GM-Tg-rg-IP2163-Ab-2Anti-Rat TOR1AIP1 monoclonal antibodyRat
GM-Tg-mg-IP2163-Ab-1/ GM-Tg-mg-IP2163-Ab-2Anti-Mouse TOR1AIP1 monoclonal antibodyMouse
GM-Tg-cynog-IP2163-Ab-1/ GM-Tg-cynog-IP2163-Ab-2Anti-Cynomolgus/ Rhesus macaque TOR1AIP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2163-Ab-1/ GM-Tg-felg-IP2163-Ab-2Anti-Feline TOR1AIP1 monoclonal antibodyFeline
GM-Tg-cang-IP2163-Ab-1/ GM-Tg-cang-IP2163-Ab-2Anti-Canine TOR1AIP1 monoclonal antibodyCanine
GM-Tg-bovg-IP2163-Ab-1/ GM-Tg-bovg-IP2163-Ab-2Anti-Bovine TOR1AIP1 monoclonal antibodyBovine
GM-Tg-equg-IP2163-Ab-1/ GM-Tg-equg-IP2163-Ab-2Anti-Equine TOR1AIP1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2163-Ab-1/ GM-Tg-hg-IP2163-Ab-2; GM-Tg-rg-IP2163-Ab-1/ GM-Tg-rg-IP2163-Ab-2;
GM-Tg-mg-IP2163-Ab-1/ GM-Tg-mg-IP2163-Ab-2; GM-Tg-cynog-IP2163-Ab-1/ GM-Tg-cynog-IP2163-Ab-2;
GM-Tg-felg-IP2163-Ab-1/ GM-Tg-felg-IP2163-Ab-2; GM-Tg-cang-IP2163-Ab-1/ GM-Tg-cang-IP2163-Ab-2;
GM-Tg-bovg-IP2163-Ab-1/ GM-Tg-bovg-IP2163-Ab-2; GM-Tg-equg-IP2163-Ab-1/ GM-Tg-equg-IP2163-Ab-2
Products NameAnti-TOR1AIP1 monoclonal antibody
Formatmab
Target NameTOR1AIP1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TOR1AIP1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2163-Ag-1Recombinant multi-species TOIP1/ TOR1AIP1/ LAP1 protein


    Target information

    Target IDGM-IP2163
    Target NameTOR1AIP1
    Gene ID26092,208263,246314,716611,610317,101095790,100052943
    Gene Symbol and SynonymsLAP1,LAP1B,LAP1C,LGMD2Y,TOR1AIP1
    Uniprot AccessionQ5JTV8,Q5PQX1
    Uniprot Entry NameTOIP1_HUMAN,TOIP1_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000143337
    Target ClassificationN/A

    The target: TOR1AIP1, gene name: TOR1AIP1, also named as LAP1, LAP1B, LGMD2Y. This gene encodes a type 2 integral membrane protein that binds A- and B-type lamins. The encoded protein localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane to the nuclear lamina during cell division. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.