- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-TPI1 monoclonal antibody
Pre-made anti-TPI1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to TPI1/TPI1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2166-Ab-1/ GM-Tg-hg-IP2166-Ab-2 | Anti-Human TPI1 monoclonal antibody | Human |
| GM-Tg-rg-IP2166-Ab-1/ GM-Tg-rg-IP2166-Ab-2 | Anti-Rat TPI1 monoclonal antibody | Rat |
| GM-Tg-mg-IP2166-Ab-1/ GM-Tg-mg-IP2166-Ab-2 | Anti-Mouse TPI1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2166-Ab-1/ GM-Tg-cynog-IP2166-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TPI1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2166-Ab-1/ GM-Tg-felg-IP2166-Ab-2 | Anti-Feline TPI1 monoclonal antibody | Feline |
| GM-Tg-cang-IP2166-Ab-1/ GM-Tg-cang-IP2166-Ab-2 | Anti-Canine TPI1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2166-Ab-1/ GM-Tg-bovg-IP2166-Ab-2 | Anti-Bovine TPI1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2166-Ab-1/ GM-Tg-equg-IP2166-Ab-2 | Anti-Equine TPI1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2166-Ab-1/ GM-Tg-hg-IP2166-Ab-2; GM-Tg-rg-IP2166-Ab-1/ GM-Tg-rg-IP2166-Ab-2; GM-Tg-mg-IP2166-Ab-1/ GM-Tg-mg-IP2166-Ab-2; GM-Tg-cynog-IP2166-Ab-1/ GM-Tg-cynog-IP2166-Ab-2; GM-Tg-felg-IP2166-Ab-1/ GM-Tg-felg-IP2166-Ab-2; GM-Tg-cang-IP2166-Ab-1/ GM-Tg-cang-IP2166-Ab-2; GM-Tg-bovg-IP2166-Ab-1/ GM-Tg-bovg-IP2166-Ab-2; GM-Tg-equg-IP2166-Ab-1/ GM-Tg-equg-IP2166-Ab-2 |
| Products Name | Anti-TPI1 monoclonal antibody |
| Format | mab |
| Target Name | TPI1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TPI1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2166-Ag-1 | Recombinant multi-species TPIS/ TPI1/ HEL-S-49 protein |
| ORF Viral Vector | vGMLP003331 | human TPI1 Lentivirus particle |
| ORF Viral Vector | pGMLP003331 | human TPI1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000985 | mouse Tpi1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000985 | mouse Tpi1 Lentivirus particle |
Target information
| Target ID | GM-IP2166 |
| Target Name | TPI1 |
| Gene ID | 7167,21991,24849,714090,477711,101085900,281543,100052671 |
| Gene Symbol and Synonyms | HEL-S-49,TIM,TPI,Tpi-1,TPI1,TPID |
| Uniprot Accession | P60174,P48500,P15426,P54714,Q5E956 |
| Uniprot Entry Name | TPIS_HUMAN,TPIS_MACMU,TPIS_RAT,TPIS_CANLF,TPIS_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Malignant neoplasm of bladder, Congenital occlusion of ureteropelvic junction |
| Gene Ensembl | ENSG00000111669 |
| Target Classification | N/A |
The target: TPI1, gene name: TPI1, also named as HEL-S-49, TIM, TPI, TPID. This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
