- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-TPSG1 monoclonal antibody
Pre-made anti-TPSG1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to TPSG1/TPSG1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2168-Ab-1/ GM-Tg-hg-IP2168-Ab-2 | Anti-Human TPSG1 monoclonal antibody | Human |
| GM-Tg-rg-IP2168-Ab-1/ GM-Tg-rg-IP2168-Ab-2 | Anti-Rat TPSG1 monoclonal antibody | Rat |
| GM-Tg-mg-IP2168-Ab-1/ GM-Tg-mg-IP2168-Ab-2 | Anti-Mouse TPSG1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2168-Ab-1/ GM-Tg-cynog-IP2168-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TPSG1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2168-Ab-1/ GM-Tg-felg-IP2168-Ab-2 | Anti-Feline TPSG1 monoclonal antibody | Feline |
| GM-Tg-cang-IP2168-Ab-1/ GM-Tg-cang-IP2168-Ab-2 | Anti-Canine TPSG1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2168-Ab-1/ GM-Tg-bovg-IP2168-Ab-2 | Anti-Bovine TPSG1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2168-Ab-1/ GM-Tg-equg-IP2168-Ab-2 | Anti-Equine TPSG1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2168-Ab-1/ GM-Tg-hg-IP2168-Ab-2; GM-Tg-rg-IP2168-Ab-1/ GM-Tg-rg-IP2168-Ab-2; GM-Tg-mg-IP2168-Ab-1/ GM-Tg-mg-IP2168-Ab-2; GM-Tg-cynog-IP2168-Ab-1/ GM-Tg-cynog-IP2168-Ab-2; GM-Tg-felg-IP2168-Ab-1/ GM-Tg-felg-IP2168-Ab-2; GM-Tg-cang-IP2168-Ab-1/ GM-Tg-cang-IP2168-Ab-2; GM-Tg-bovg-IP2168-Ab-1/ GM-Tg-bovg-IP2168-Ab-2; GM-Tg-equg-IP2168-Ab-1/ GM-Tg-equg-IP2168-Ab-2 |
| Products Name | Anti-TPSG1 monoclonal antibody |
| Format | mab |
| Target Name | TPSG1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TPSG1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2168-Ag-1 | Recombinant multi-species TRYG1/ TPSG1/ PRSS31 protein |
Target information
| Target ID | GM-IP2168 |
| Target Name | TPSG1 |
| Gene ID | 25823,26945,302990,100425751,100067538 |
| Gene Symbol and Synonyms | PRSS31,™T,TPSG1,trpA |
| Uniprot Accession | Q9NRR2 |
| Uniprot Entry Name | TRYG1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000116176 |
| Target Classification | N/A |
The target: TPSG1, gene name: TPSG1, also named as PRSS31, ™T, trpA. Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
