Anti-TSPAN2 monoclonal antibody

Pre-made anti-TSPAN2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TSPAN2/TSPAN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2190-Ab-1/ GM-Tg-hg-IP2190-Ab-2Anti-Human TSPAN2 monoclonal antibodyHuman
GM-Tg-rg-IP2190-Ab-1/ GM-Tg-rg-IP2190-Ab-2Anti-Rat TSPAN2 monoclonal antibodyRat
GM-Tg-mg-IP2190-Ab-1/ GM-Tg-mg-IP2190-Ab-2Anti-Mouse TSPAN2 monoclonal antibodyMouse
GM-Tg-cynog-IP2190-Ab-1/ GM-Tg-cynog-IP2190-Ab-2Anti-Cynomolgus/ Rhesus macaque TSPAN2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2190-Ab-1/ GM-Tg-felg-IP2190-Ab-2Anti-Feline TSPAN2 monoclonal antibodyFeline
GM-Tg-cang-IP2190-Ab-1/ GM-Tg-cang-IP2190-Ab-2Anti-Canine TSPAN2 monoclonal antibodyCanine
GM-Tg-bovg-IP2190-Ab-1/ GM-Tg-bovg-IP2190-Ab-2Anti-Bovine TSPAN2 monoclonal antibodyBovine
GM-Tg-equg-IP2190-Ab-1/ GM-Tg-equg-IP2190-Ab-2Anti-Equine TSPAN2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2190-Ab-1/ GM-Tg-hg-IP2190-Ab-2; GM-Tg-rg-IP2190-Ab-1/ GM-Tg-rg-IP2190-Ab-2;
GM-Tg-mg-IP2190-Ab-1/ GM-Tg-mg-IP2190-Ab-2; GM-Tg-cynog-IP2190-Ab-1/ GM-Tg-cynog-IP2190-Ab-2;
GM-Tg-felg-IP2190-Ab-1/ GM-Tg-felg-IP2190-Ab-2; GM-Tg-cang-IP2190-Ab-1/ GM-Tg-cang-IP2190-Ab-2;
GM-Tg-bovg-IP2190-Ab-1/ GM-Tg-bovg-IP2190-Ab-2; GM-Tg-equg-IP2190-Ab-1/ GM-Tg-equg-IP2190-Ab-2
Products NameAnti-TSPAN2 monoclonal antibody
Formatmab
Target NameTSPAN2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TSPAN2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2190-Ag-1Recombinant multi-species TSN2/ TSPAN2/ NET3 protein


    Target information

    Target IDGM-IP2190
    Target NameTSPAN2
    Gene ID10100,70747,64521,709463,612755,101097627,539001,100065606
    Gene Symbol and Synonyms6330415F13Rik,B230119D02Rik,NET3,TSN2,TSPAN-2,TSPAN2
    Uniprot AccessionO60636,Q9JJW1
    Uniprot Entry NameTSN2_HUMAN,TSN2_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseProstate Cancer
    Gene EnsemblENSG00000134198
    Target ClassificationN/A

    The target: TSPAN2, gene name: TSPAN2, also named as NET3, TSN2, TSPAN-2. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.