Anti-TSSK4 monoclonal antibody

Pre-made anti-TSSK4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TSSK4/TSSK4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2197-Ab-1/ GM-Tg-hg-IP2197-Ab-2Anti-Human TSSK4 monoclonal antibodyHuman
GM-Tg-rg-IP2197-Ab-1/ GM-Tg-rg-IP2197-Ab-2Anti-Rat TSSK4 monoclonal antibodyRat
GM-Tg-mg-IP2197-Ab-1/ GM-Tg-mg-IP2197-Ab-2Anti-Mouse TSSK4 monoclonal antibodyMouse
GM-Tg-cynog-IP2197-Ab-1/ GM-Tg-cynog-IP2197-Ab-2Anti-Cynomolgus/ Rhesus macaque TSSK4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2197-Ab-1/ GM-Tg-felg-IP2197-Ab-2Anti-Feline TSSK4 monoclonal antibodyFeline
GM-Tg-cang-IP2197-Ab-1/ GM-Tg-cang-IP2197-Ab-2Anti-Canine TSSK4 monoclonal antibodyCanine
GM-Tg-bovg-IP2197-Ab-1/ GM-Tg-bovg-IP2197-Ab-2Anti-Bovine TSSK4 monoclonal antibodyBovine
GM-Tg-equg-IP2197-Ab-1/ GM-Tg-equg-IP2197-Ab-2Anti-Equine TSSK4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2197-Ab-1/ GM-Tg-hg-IP2197-Ab-2; GM-Tg-rg-IP2197-Ab-1/ GM-Tg-rg-IP2197-Ab-2;
GM-Tg-mg-IP2197-Ab-1/ GM-Tg-mg-IP2197-Ab-2; GM-Tg-cynog-IP2197-Ab-1/ GM-Tg-cynog-IP2197-Ab-2;
GM-Tg-felg-IP2197-Ab-1/ GM-Tg-felg-IP2197-Ab-2; GM-Tg-cang-IP2197-Ab-1/ GM-Tg-cang-IP2197-Ab-2;
GM-Tg-bovg-IP2197-Ab-1/ GM-Tg-bovg-IP2197-Ab-2; GM-Tg-equg-IP2197-Ab-1/ GM-Tg-equg-IP2197-Ab-2
Products NameAnti-TSSK4 monoclonal antibody
Formatmab
Target NameTSSK4
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TSSK4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2197-Ag-1Recombinant multi-species TSSK4/ C14orf20/ STK22E protein


    Target information

    Target IDGM-IP2197
    Target NameTSSK4
    Gene ID283629,71099,290229,715578,480262,101080294,539477,100051378
    Gene Symbol and Synonyms1700020B19Rik,4933424F08Rik,C14orf20,RGD1560814,STK22E,TSK-4,TSK4,TSSK-4,TSSK4,TSSK5
    Uniprot AccessionQ6SA08
    Uniprot Entry NameTSSK4_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseOvary Cancer
    Gene EnsemblENSG00000139908
    Target ClassificationKinase

    The target: TSSK4, gene name: TSSK4, also named as C14orf20, STK22E, TSK-4, TSK4, TSSK5. This gene encodes a member of the testis-specific serine/threonine kinase family. The encoded protein is thought to be involved in spermatogenesis via stimulation of the CREB/CRE responsive pathway through phosphorylation of the cAMP responsive element binding protein transcription factor. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.