Anti-TTC39B monoclonal antibody

Pre-made anti-TTC39B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TTC39B/TTC39B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2202-Ab-1/ GM-Tg-hg-IP2202-Ab-2Anti-Human TTC39B monoclonal antibodyHuman
GM-Tg-rg-IP2202-Ab-1/ GM-Tg-rg-IP2202-Ab-2Anti-Rat TTC39B monoclonal antibodyRat
GM-Tg-mg-IP2202-Ab-1/ GM-Tg-mg-IP2202-Ab-2Anti-Mouse TTC39B monoclonal antibodyMouse
GM-Tg-cynog-IP2202-Ab-1/ GM-Tg-cynog-IP2202-Ab-2Anti-Cynomolgus/ Rhesus macaque TTC39B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2202-Ab-1/ GM-Tg-felg-IP2202-Ab-2Anti-Feline TTC39B monoclonal antibodyFeline
GM-Tg-cang-IP2202-Ab-1/ GM-Tg-cang-IP2202-Ab-2Anti-Canine TTC39B monoclonal antibodyCanine
GM-Tg-bovg-IP2202-Ab-1/ GM-Tg-bovg-IP2202-Ab-2Anti-Bovine TTC39B monoclonal antibodyBovine
GM-Tg-equg-IP2202-Ab-1/ GM-Tg-equg-IP2202-Ab-2Anti-Equine TTC39B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2202-Ab-1/ GM-Tg-hg-IP2202-Ab-2; GM-Tg-rg-IP2202-Ab-1/ GM-Tg-rg-IP2202-Ab-2;
GM-Tg-mg-IP2202-Ab-1/ GM-Tg-mg-IP2202-Ab-2; GM-Tg-cynog-IP2202-Ab-1/ GM-Tg-cynog-IP2202-Ab-2;
GM-Tg-felg-IP2202-Ab-1/ GM-Tg-felg-IP2202-Ab-2; GM-Tg-cang-IP2202-Ab-1/ GM-Tg-cang-IP2202-Ab-2;
GM-Tg-bovg-IP2202-Ab-1/ GM-Tg-bovg-IP2202-Ab-2; GM-Tg-equg-IP2202-Ab-1/ GM-Tg-equg-IP2202-Ab-2
Products NameAnti-TTC39B monoclonal antibody
Formatmab
Target NameTTC39B
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TTC39B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2202-Ag-1Recombinant multi-species TT39B/ TTC39B/ C9orf52 protein


    Target information

    Target IDGM-IP2202
    Target NameTTC39B
    Gene ID158219,69863,298186,714876,474710,101096423,508428,100062430
    Gene Symbol and Synonyms1810054D07Rik,9130422G05Rik,C9orf52,RGD1305797,TTC39B
    Uniprot AccessionQ5VTQ0,D3ZC96
    Uniprot Entry NameTT39B_HUMAN,TT39B_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000155158
    Target ClassificationN/A

    The target: TTC39B, gene name: TTC39B, also named as C9orf52. Predicted to be involved in several processes, including cholesterol homeostasis; negative regulation of cholesterol storage; and regulation of cholesterol efflux. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.