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Anti-TUBB3 monoclonal antibody
Pre-made anti-TUBB3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to TUBB3/TUBB3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2208-Ab-1/ GM-Tg-hg-IP2208-Ab-2 | Anti-Human TUBB3 monoclonal antibody | Human |
| GM-Tg-rg-IP2208-Ab-1/ GM-Tg-rg-IP2208-Ab-2 | Anti-Rat TUBB3 monoclonal antibody | Rat |
| GM-Tg-mg-IP2208-Ab-1/ GM-Tg-mg-IP2208-Ab-2 | Anti-Mouse TUBB3 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2208-Ab-1/ GM-Tg-cynog-IP2208-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TUBB3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2208-Ab-1/ GM-Tg-felg-IP2208-Ab-2 | Anti-Feline TUBB3 monoclonal antibody | Feline |
| GM-Tg-cang-IP2208-Ab-1/ GM-Tg-cang-IP2208-Ab-2 | Anti-Canine TUBB3 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2208-Ab-1/ GM-Tg-bovg-IP2208-Ab-2 | Anti-Bovine TUBB3 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2208-Ab-1/ GM-Tg-equg-IP2208-Ab-2 | Anti-Equine TUBB3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2208-Ab-1/ GM-Tg-hg-IP2208-Ab-2; GM-Tg-rg-IP2208-Ab-1/ GM-Tg-rg-IP2208-Ab-2; GM-Tg-mg-IP2208-Ab-1/ GM-Tg-mg-IP2208-Ab-2; GM-Tg-cynog-IP2208-Ab-1/ GM-Tg-cynog-IP2208-Ab-2; GM-Tg-felg-IP2208-Ab-1/ GM-Tg-felg-IP2208-Ab-2; GM-Tg-cang-IP2208-Ab-1/ GM-Tg-cang-IP2208-Ab-2; GM-Tg-bovg-IP2208-Ab-1/ GM-Tg-bovg-IP2208-Ab-2; GM-Tg-equg-IP2208-Ab-1/ GM-Tg-equg-IP2208-Ab-2 |
| Products Name | Anti-TUBB3 monoclonal antibody |
| Format | mab |
| Target Name | TUBB3 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TUBB3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2208-Ag-1 | Recombinant multi-species TBB3/ TUBB3/ CDCBM protein |
| ORF Viral Vector | vGMLP000317 | human TUBB3 Lentivirus particle |
| ORF Viral Vector | pGMLP000317 | human TUBB3 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002661 | mouse Tubb3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002661 | mouse Tubb3 Lentivirus particle |
Target information
| Target ID | GM-IP2208 |
| Target Name | TUBB3 |
| Gene ID | 10381,22152,246118,768070,111772826 |
| Gene Symbol and Synonyms | 3200002H15Rik,beta-4,CDCBM,CDCBM1,CFEOM3,CFEOM3A,FEOM3,M(beta)3,M(beta)6,TUBB3,TUBB4 |
| Uniprot Accession | Q13509,Q4QRB4,Q2T9S0 |
| Uniprot Entry Name | TBB3_HUMAN,TBB3_RAT,TBB3_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000258947 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: TUBB3, gene name: TUBB3, also named as CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4. This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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