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Anti-TUBB4A monoclonal antibody
Pre-made anti-TUBB4A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to TUBB4A/TUBB4A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2209-Ab-1/ GM-Tg-hg-IP2209-Ab-2 | Anti-Human TUBB4A monoclonal antibody | Human |
| GM-Tg-rg-IP2209-Ab-1/ GM-Tg-rg-IP2209-Ab-2 | Anti-Rat TUBB4A monoclonal antibody | Rat |
| GM-Tg-mg-IP2209-Ab-1/ GM-Tg-mg-IP2209-Ab-2 | Anti-Mouse TUBB4A monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2209-Ab-1/ GM-Tg-cynog-IP2209-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TUBB4A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2209-Ab-1/ GM-Tg-felg-IP2209-Ab-2 | Anti-Feline TUBB4A monoclonal antibody | Feline |
| GM-Tg-cang-IP2209-Ab-1/ GM-Tg-cang-IP2209-Ab-2 | Anti-Canine TUBB4A monoclonal antibody | Canine |
| GM-Tg-bovg-IP2209-Ab-1/ GM-Tg-bovg-IP2209-Ab-2 | Anti-Bovine TUBB4A monoclonal antibody | Bovine |
| GM-Tg-equg-IP2209-Ab-1/ GM-Tg-equg-IP2209-Ab-2 | Anti-Equine TUBB4A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2209-Ab-1/ GM-Tg-hg-IP2209-Ab-2; GM-Tg-rg-IP2209-Ab-1/ GM-Tg-rg-IP2209-Ab-2; GM-Tg-mg-IP2209-Ab-1/ GM-Tg-mg-IP2209-Ab-2; GM-Tg-cynog-IP2209-Ab-1/ GM-Tg-cynog-IP2209-Ab-2; GM-Tg-felg-IP2209-Ab-1/ GM-Tg-felg-IP2209-Ab-2; GM-Tg-cang-IP2209-Ab-1/ GM-Tg-cang-IP2209-Ab-2; GM-Tg-bovg-IP2209-Ab-1/ GM-Tg-bovg-IP2209-Ab-2; GM-Tg-equg-IP2209-Ab-1/ GM-Tg-equg-IP2209-Ab-2 |
| Products Name | Anti-TUBB4A monoclonal antibody |
| Format | mab |
| Target Name | TUBB4A |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TUBB4A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2209-Ag-1 | Recombinant multi-species TBB4A/ TUBB4A/ DYT4 protein |
| ORF Viral Vector | vGMLP003701 | human TUBB4A Lentivirus particle |
| ORF Viral Vector | pGMLP003701 | human TUBB4A Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002655 | mouse Tubb4a Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004885 | mouse Tubb4a Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002655 | mouse Tubb4a Lentivirus particle |
| ORF Viral Vector | vGMLPm004885 | mouse Tubb4a Lentivirus particle |
Target information
| Target ID | GM-IP2209 |
| Target Name | TUBB4A |
| Gene ID | 10382,22153,29213,703019,100855815,101086953,540236,100065776 |
| Gene Symbol and Synonyms | beta-5,DYT4,M(beta)4,Tubb,TUBB4,TUBB4A |
| Uniprot Accession | P04350,Q3ZBU7 |
| Uniprot Entry Name | TBB4A_HUMAN,TBB4A_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000104833 |
| Target Classification | N/A |
The target: TUBB4A, gene name: TUBB4A, also named as DYT4, TUBB4, beta-5. This gene encodes a member of the beta tubulin family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene cause hypomyelinating leukodystrophy-6 and autosomal dominant torsion dystonia-4. Alternate splicing results in multiple transcript variants encoding different isoforms. A pseudogene of this gene is found on chromosome X. [provided by RefSeq, Jan 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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