Anti-TVP23C-CDRT4 monoclonal antibody

Pre-made anti-TVP23C-CDRT4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TVP23C-CDRT4/TVP23C-CDRT4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2214-Ab-1/ GM-Tg-hg-IP2214-Ab-2Anti-Human TVP23C-CDRT4 monoclonal antibodyHuman
GM-Tg-rg-IP2214-Ab-1/ GM-Tg-rg-IP2214-Ab-2Anti-Rat TVP23C-CDRT4 monoclonal antibodyRat
GM-Tg-mg-IP2214-Ab-1/ GM-Tg-mg-IP2214-Ab-2Anti-Mouse TVP23C-CDRT4 monoclonal antibodyMouse
GM-Tg-cynog-IP2214-Ab-1/ GM-Tg-cynog-IP2214-Ab-2Anti-Cynomolgus/ Rhesus macaque TVP23C-CDRT4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2214-Ab-1/ GM-Tg-felg-IP2214-Ab-2Anti-Feline TVP23C-CDRT4 monoclonal antibodyFeline
GM-Tg-cang-IP2214-Ab-1/ GM-Tg-cang-IP2214-Ab-2Anti-Canine TVP23C-CDRT4 monoclonal antibodyCanine
GM-Tg-bovg-IP2214-Ab-1/ GM-Tg-bovg-IP2214-Ab-2Anti-Bovine TVP23C-CDRT4 monoclonal antibodyBovine
GM-Tg-equg-IP2214-Ab-1/ GM-Tg-equg-IP2214-Ab-2Anti-Equine TVP23C-CDRT4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2214-Ab-1/ GM-Tg-hg-IP2214-Ab-2; GM-Tg-rg-IP2214-Ab-1/ GM-Tg-rg-IP2214-Ab-2;
GM-Tg-mg-IP2214-Ab-1/ GM-Tg-mg-IP2214-Ab-2; GM-Tg-cynog-IP2214-Ab-1/ GM-Tg-cynog-IP2214-Ab-2;
GM-Tg-felg-IP2214-Ab-1/ GM-Tg-felg-IP2214-Ab-2; GM-Tg-cang-IP2214-Ab-1/ GM-Tg-cang-IP2214-Ab-2;
GM-Tg-bovg-IP2214-Ab-1/ GM-Tg-bovg-IP2214-Ab-2; GM-Tg-equg-IP2214-Ab-1/ GM-Tg-equg-IP2214-Ab-2
Products NameAnti-TVP23C-CDRT4 monoclonal antibody
Formatmab
Target NameTVP23C-CDRT4
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TVP23C-CDRT4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2214-Ag-1Recombinant multi-species TVP23C-CDRT4/ FAM18B2/ FAM18B2-CDRT4 protein


    Target information

    Target IDGM-IP2214
    Target NameTVP23C-CDRT4
    Gene ID100533496
    Gene Symbol and SynonymsFAM18B2,FAM18B2-CDRT4,TVP23C,TVP23C-CDRT4
    Uniprot AccessionN/A
    Uniprot Entry Name
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000259024
    Target ClassificationN/A

    The target: TVP23C-CDRT4, gene name: TVP23C-CDRT4, also named as FAM18B2, FAM18B2-CDRT4, TVP23C. This locus represents naturally occurring readthrough transcription between the neighboring TVP23C (trans-golgi network vesicle protein 23 homolog) and CDRT4 (CMT1A duplicated region transcript 4) genes on chromosome 17. Alternative splicing results in multiple transcript variants, one of which encodes a protein that shares sequence identity with the upstream gene product, but its C-terminus is distinct due to frameshifts relative to the downstream gene. [provided by RefSeq, Apr 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.