Anti-UBA5 monoclonal antibody

Pre-made anti-UBA5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to UBA5/UBA5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2218-Ab-1/ GM-Tg-hg-IP2218-Ab-2Anti-Human UBA5 monoclonal antibodyHuman
GM-Tg-rg-IP2218-Ab-1/ GM-Tg-rg-IP2218-Ab-2Anti-Rat UBA5 monoclonal antibodyRat
GM-Tg-mg-IP2218-Ab-1/ GM-Tg-mg-IP2218-Ab-2Anti-Mouse UBA5 monoclonal antibodyMouse
GM-Tg-cynog-IP2218-Ab-1/ GM-Tg-cynog-IP2218-Ab-2Anti-Cynomolgus/ Rhesus macaque UBA5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2218-Ab-1/ GM-Tg-felg-IP2218-Ab-2Anti-Feline UBA5 monoclonal antibodyFeline
GM-Tg-cang-IP2218-Ab-1/ GM-Tg-cang-IP2218-Ab-2Anti-Canine UBA5 monoclonal antibodyCanine
GM-Tg-bovg-IP2218-Ab-1/ GM-Tg-bovg-IP2218-Ab-2Anti-Bovine UBA5 monoclonal antibodyBovine
GM-Tg-equg-IP2218-Ab-1/ GM-Tg-equg-IP2218-Ab-2Anti-Equine UBA5 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2218-Ab-1/ GM-Tg-hg-IP2218-Ab-2; GM-Tg-rg-IP2218-Ab-1/ GM-Tg-rg-IP2218-Ab-2;
GM-Tg-mg-IP2218-Ab-1/ GM-Tg-mg-IP2218-Ab-2; GM-Tg-cynog-IP2218-Ab-1/ GM-Tg-cynog-IP2218-Ab-2;
GM-Tg-felg-IP2218-Ab-1/ GM-Tg-felg-IP2218-Ab-2; GM-Tg-cang-IP2218-Ab-1/ GM-Tg-cang-IP2218-Ab-2;
GM-Tg-bovg-IP2218-Ab-1/ GM-Tg-bovg-IP2218-Ab-2; GM-Tg-equg-IP2218-Ab-1/ GM-Tg-equg-IP2218-Ab-2
Products NameAnti-UBA5 monoclonal antibody
Formatmab
Target NameUBA5
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-UBA5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2218-Ag-1Recombinant multi-species UBA5/ EIEE44/ SCAR24 protein


    Target information

    Target IDGM-IP2218
    Target NameUBA5
    Gene ID79876,66663,300968,717647,100856526,101088609,509292,100052911
    Gene Symbol and Synonyms5730525G14Rik,DEE44,EIEE44,SCAR24,THIFP1,UBA5,UBE1DC1
    Uniprot AccessionQ9GZZ9,Q5M7A4,A7MAZ3
    Uniprot Entry NameUBA5_HUMAN,UBA5_RAT,UBA5_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000081307
    Target ClassificationN/A

    The target: UBA5, gene name: UBA5, also named as EIEE44, SCAR24, THIFP1, UBE1DC1. This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been identified on chromosome 1. [provided by RefSeq, Feb 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.