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Anti-UGT2A1 monoclonal antibody
Pre-made anti-UGT2A1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to UGT2A1/UGT2A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2232-Ab-1/ GM-Tg-hg-IP2232-Ab-2 | Anti-Human UGT2A1 monoclonal antibody | Human |
| GM-Tg-rg-IP2232-Ab-1/ GM-Tg-rg-IP2232-Ab-2 | Anti-Rat UGT2A1 monoclonal antibody | Rat |
| GM-Tg-mg-IP2232-Ab-1/ GM-Tg-mg-IP2232-Ab-2 | Anti-Mouse UGT2A1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2232-Ab-1/ GM-Tg-cynog-IP2232-Ab-2 | Anti-Cynomolgus/ Rhesus macaque UGT2A1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2232-Ab-1/ GM-Tg-felg-IP2232-Ab-2 | Anti-Feline UGT2A1 monoclonal antibody | Feline |
| GM-Tg-cang-IP2232-Ab-1/ GM-Tg-cang-IP2232-Ab-2 | Anti-Canine UGT2A1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2232-Ab-1/ GM-Tg-bovg-IP2232-Ab-2 | Anti-Bovine UGT2A1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2232-Ab-1/ GM-Tg-equg-IP2232-Ab-2 | Anti-Equine UGT2A1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2232-Ab-1/ GM-Tg-hg-IP2232-Ab-2; GM-Tg-rg-IP2232-Ab-1/ GM-Tg-rg-IP2232-Ab-2; GM-Tg-mg-IP2232-Ab-1/ GM-Tg-mg-IP2232-Ab-2; GM-Tg-cynog-IP2232-Ab-1/ GM-Tg-cynog-IP2232-Ab-2; GM-Tg-felg-IP2232-Ab-1/ GM-Tg-felg-IP2232-Ab-2; GM-Tg-cang-IP2232-Ab-1/ GM-Tg-cang-IP2232-Ab-2; GM-Tg-bovg-IP2232-Ab-1/ GM-Tg-bovg-IP2232-Ab-2; GM-Tg-equg-IP2232-Ab-1/ GM-Tg-equg-IP2232-Ab-2 |
| Products Name | Anti-UGT2A1 monoclonal antibody |
| Format | mab |
| Target Name | UGT2A1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-UGT2A1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2232-Ag-1 | Recombinant multi-species UD2A1/ UGT2A1/ UDPGT2A1 protein |
Target information
| Target ID | GM-IP2232 |
| Target Name | UGT2A1 |
| Gene ID | 10941 |
| Gene Symbol and Synonyms | UDPGT2A1,UGT2A1 |
| Uniprot Accession | P0DTE4 |
| Uniprot Entry Name | UD2A1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000173610 |
| Target Classification | N/A |
The target: UGT2A1, gene name: UGT2A1, also named as UDPGT2A1. The protein encoded by this gene belongs to the UDP-glycosyltransferase family. Members of this protein family play a role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. The encoded enzyme is expressed in the olfactory neuroepithelium, which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence, this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium. This gene shares exon structure with the UDP glucuronosyltransferase 2A2 family member, which encodes N-terminally distinct isoforms. Polymorphisms in this gene may be associated with the loss of taste and smell that is reported by some individuals during SARS-CoV-2 infection. [provided by RefSeq, Jan 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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