Anti-UGT2B7 monoclonal antibody

Pre-made anti-UGT2B7 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to UGT2B7/UGT2B7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2239-Ab-1/ GM-Tg-hg-IP2239-Ab-2Anti-Human UGT2B7 monoclonal antibodyHuman
GM-Tg-rg-IP2239-Ab-1/ GM-Tg-rg-IP2239-Ab-2Anti-Rat UGT2B7 monoclonal antibodyRat
GM-Tg-mg-IP2239-Ab-1/ GM-Tg-mg-IP2239-Ab-2Anti-Mouse UGT2B7 monoclonal antibodyMouse
GM-Tg-cynog-IP2239-Ab-1/ GM-Tg-cynog-IP2239-Ab-2Anti-Cynomolgus/ Rhesus macaque UGT2B7 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2239-Ab-1/ GM-Tg-felg-IP2239-Ab-2Anti-Feline UGT2B7 monoclonal antibodyFeline
GM-Tg-cang-IP2239-Ab-1/ GM-Tg-cang-IP2239-Ab-2Anti-Canine UGT2B7 monoclonal antibodyCanine
GM-Tg-bovg-IP2239-Ab-1/ GM-Tg-bovg-IP2239-Ab-2Anti-Bovine UGT2B7 monoclonal antibodyBovine
GM-Tg-equg-IP2239-Ab-1/ GM-Tg-equg-IP2239-Ab-2Anti-Equine UGT2B7 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2239-Ab-1/ GM-Tg-hg-IP2239-Ab-2; GM-Tg-rg-IP2239-Ab-1/ GM-Tg-rg-IP2239-Ab-2;
GM-Tg-mg-IP2239-Ab-1/ GM-Tg-mg-IP2239-Ab-2; GM-Tg-cynog-IP2239-Ab-1/ GM-Tg-cynog-IP2239-Ab-2;
GM-Tg-felg-IP2239-Ab-1/ GM-Tg-felg-IP2239-Ab-2; GM-Tg-cang-IP2239-Ab-1/ GM-Tg-cang-IP2239-Ab-2;
GM-Tg-bovg-IP2239-Ab-1/ GM-Tg-bovg-IP2239-Ab-2; GM-Tg-equg-IP2239-Ab-1/ GM-Tg-equg-IP2239-Ab-2
Products NameAnti-UGT2B7 monoclonal antibody
Formatmab
Target NameUGT2B7
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-UGT2B7 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2239-Ag-1Recombinant multi-species UD2B7/ UGT2B7/ UDPGT 2B7 protein


    Target information

    Target IDGM-IP2239
    Target NameUGT2B7
    Gene ID7364,708989
    Gene Symbol and SynonymsUDPGT 2B7,UDPGT 2B9,UDPGT2B7,UDPGTh-2,UDPGTH2,UGT2B7,UGT2B9
    Uniprot AccessionP16662
    Uniprot Entry NameUD2B7_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000171234
    Target ClassificationN/A

    The target: UGT2B7, gene name: UGT2B7, also named as UDPGT 2B7, UDPGT 2B9, UDPGT2B7, UDPGTH2, UDPGTh-2, UGT2B9. The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.