Anti-ULK4 monoclonal antibody
Pre-made anti-ULK4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP2242-Ab-1/ GM-Tg-hg-IP2242-Ab-2 | Anti-Human ULK4 monoclonal antibody | Human |
GM-Tg-rg-IP2242-Ab-1/ GM-Tg-rg-IP2242-Ab-2 | Anti-Rat ULK4 monoclonal antibody | Rat |
GM-Tg-mg-IP2242-Ab-1/ GM-Tg-mg-IP2242-Ab-2 | Anti-Mouse ULK4 monoclonal antibody | Mouse |
GM-Tg-cynog-IP2242-Ab-1/ GM-Tg-cynog-IP2242-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ULK4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP2242-Ab-1/ GM-Tg-felg-IP2242-Ab-2 | Anti-Feline ULK4 monoclonal antibody | Feline |
GM-Tg-cang-IP2242-Ab-1/ GM-Tg-cang-IP2242-Ab-2 | Anti-Canine ULK4 monoclonal antibody | Canine |
GM-Tg-bovg-IP2242-Ab-1/ GM-Tg-bovg-IP2242-Ab-2 | Anti-Bovine ULK4 monoclonal antibody | Bovine |
GM-Tg-equg-IP2242-Ab-1/ GM-Tg-equg-IP2242-Ab-2 | Anti-Equine ULK4 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-IP2242-Ab-1/ GM-Tg-hg-IP2242-Ab-2; GM-Tg-rg-IP2242-Ab-1/ GM-Tg-rg-IP2242-Ab-2; GM-Tg-mg-IP2242-Ab-1/ GM-Tg-mg-IP2242-Ab-2; GM-Tg-cynog-IP2242-Ab-1/ GM-Tg-cynog-IP2242-Ab-2; GM-Tg-felg-IP2242-Ab-1/ GM-Tg-felg-IP2242-Ab-2; GM-Tg-cang-IP2242-Ab-1/ GM-Tg-cang-IP2242-Ab-2; GM-Tg-bovg-IP2242-Ab-1/ GM-Tg-bovg-IP2242-Ab-2; GM-Tg-equg-IP2242-Ab-1/ GM-Tg-equg-IP2242-Ab-2 |
Products Name | Anti-ULK4 monoclonal antibody |
Format | mab |
Target Name | ULK4 |
Protein Sub-location | Introcelluar Protein |
Category of antibody | |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-ULK4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-IP2242-Ag-1 | Recombinant multi-species ULK4/ FAM7C1/ REC01035 protein |
Target information
Target ID | GM-IP2242 |
Target Name | ULK4 |
Gene ID | 54986,209012,363167,717956,477033,101082773,100336480,100067713 |
Gene Symbol and Synonyms | 4932415A06Rik,A730098P15,FAM7C1,REC01035,RGD1565726,ULK4 |
Uniprot Accession | Q96C45 |
Uniprot Entry Name | ULK4_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000168038 |
Target Classification | Kinase |
The target: ULK4, gene name: ULK4, also named as FAM7C1, REC01035. This gene encodes a member of the unc-51-like serine/threonine kinase (STK) family. Members of this protein family play a role in neuronal growth and endocytosis. The encoded protein is likely involved in neurite branching, neurite elongation and neuronal migration. Genome-wide association studies (GWAS) indicate an association of variations in this gene with blood pressure and hypertension. Sequence variations in this gene may also be be associated with psychiatric disorders, including schizophrenia and bipolar disorder. Pseudogenes associated with this gene have been identified and are located on chromosome 15. [provided by RefSeq, Jul 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.