Anti-UNC50 monoclonal antibody

Pre-made anti-UNC50 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to UNC50/UNC50 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2244-Ab-1/ GM-Tg-hg-IP2244-Ab-2Anti-Human UNC50 monoclonal antibodyHuman
GM-Tg-rg-IP2244-Ab-1/ GM-Tg-rg-IP2244-Ab-2Anti-Rat UNC50 monoclonal antibodyRat
GM-Tg-mg-IP2244-Ab-1/ GM-Tg-mg-IP2244-Ab-2Anti-Mouse UNC50 monoclonal antibodyMouse
GM-Tg-cynog-IP2244-Ab-1/ GM-Tg-cynog-IP2244-Ab-2Anti-Cynomolgus/ Rhesus macaque UNC50 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2244-Ab-1/ GM-Tg-felg-IP2244-Ab-2Anti-Feline UNC50 monoclonal antibodyFeline
GM-Tg-cang-IP2244-Ab-1/ GM-Tg-cang-IP2244-Ab-2Anti-Canine UNC50 monoclonal antibodyCanine
GM-Tg-bovg-IP2244-Ab-1/ GM-Tg-bovg-IP2244-Ab-2Anti-Bovine UNC50 monoclonal antibodyBovine
GM-Tg-equg-IP2244-Ab-1/ GM-Tg-equg-IP2244-Ab-2Anti-Equine UNC50 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2244-Ab-1/ GM-Tg-hg-IP2244-Ab-2; GM-Tg-rg-IP2244-Ab-1/ GM-Tg-rg-IP2244-Ab-2;
GM-Tg-mg-IP2244-Ab-1/ GM-Tg-mg-IP2244-Ab-2; GM-Tg-cynog-IP2244-Ab-1/ GM-Tg-cynog-IP2244-Ab-2;
GM-Tg-felg-IP2244-Ab-1/ GM-Tg-felg-IP2244-Ab-2; GM-Tg-cang-IP2244-Ab-1/ GM-Tg-cang-IP2244-Ab-2;
GM-Tg-bovg-IP2244-Ab-1/ GM-Tg-bovg-IP2244-Ab-2; GM-Tg-equg-IP2244-Ab-1/ GM-Tg-equg-IP2244-Ab-2
Products NameAnti-UNC50 monoclonal antibody
Formatmab
Target NameUNC50
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-UNC50 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2244-Ag-1Recombinant multi-species UNC50/ GMH1/ HSD23 protein


    Target information

    Target IDGM-IP2244
    Target NameUNC50
    Gene ID25972,67387,192356,677700,611651,101088401,513629,100061121
    Gene Symbol and Synonyms1110002A21Rik,GMH1,HSD23,PDLs22,UNC50,UNCL,URP
    Uniprot AccessionQ53HI1,O55227,Q3ZBG6
    Uniprot Entry NameUNC50_HUMAN,UNC50_RAT,UNC50_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000115446
    Target ClassificationN/A

    The target: UNC50, gene name: UNC50, also named as GMH1, HSD23, PDLs22, UNCL, URP. Predicted to enable RNA binding activity. Predicted to be involved in protein localization to cell surface. Predicted to be located in Golgi apparatus and nuclear inner membrane. Predicted to be integral component of Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.