Anti-UPK2 monoclonal antibody

Pre-made anti-UPK2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to UPK2/UPK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2248-Ab-1/ GM-Tg-hg-IP2248-Ab-2Anti-Human UPK2 monoclonal antibodyHuman
GM-Tg-rg-IP2248-Ab-1/ GM-Tg-rg-IP2248-Ab-2Anti-Rat UPK2 monoclonal antibodyRat
GM-Tg-mg-IP2248-Ab-1/ GM-Tg-mg-IP2248-Ab-2Anti-Mouse UPK2 monoclonal antibodyMouse
GM-Tg-cynog-IP2248-Ab-1/ GM-Tg-cynog-IP2248-Ab-2Anti-Cynomolgus/ Rhesus macaque UPK2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2248-Ab-1/ GM-Tg-felg-IP2248-Ab-2Anti-Feline UPK2 monoclonal antibodyFeline
GM-Tg-cang-IP2248-Ab-1/ GM-Tg-cang-IP2248-Ab-2Anti-Canine UPK2 monoclonal antibodyCanine
GM-Tg-bovg-IP2248-Ab-1/ GM-Tg-bovg-IP2248-Ab-2Anti-Bovine UPK2 monoclonal antibodyBovine
GM-Tg-equg-IP2248-Ab-1/ GM-Tg-equg-IP2248-Ab-2Anti-Equine UPK2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2248-Ab-1/ GM-Tg-hg-IP2248-Ab-2; GM-Tg-rg-IP2248-Ab-1/ GM-Tg-rg-IP2248-Ab-2;
GM-Tg-mg-IP2248-Ab-1/ GM-Tg-mg-IP2248-Ab-2; GM-Tg-cynog-IP2248-Ab-1/ GM-Tg-cynog-IP2248-Ab-2;
GM-Tg-felg-IP2248-Ab-1/ GM-Tg-felg-IP2248-Ab-2; GM-Tg-cang-IP2248-Ab-1/ GM-Tg-cang-IP2248-Ab-2;
GM-Tg-bovg-IP2248-Ab-1/ GM-Tg-bovg-IP2248-Ab-2; GM-Tg-equg-IP2248-Ab-1/ GM-Tg-equg-IP2248-Ab-2
Products NameAnti-UPK2 monoclonal antibody
Formatmab
Target NameUPK2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-UPK2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2248-Ag-1Recombinant multi-species UPK2/ UP2/ UPII protein


    Target information

    Target IDGM-IP2248
    Target NameUPK2
    Gene ID7379,22269,689093,707184,610673,101093136,281569,100063180
    Gene Symbol and SynonymsUP2,UPII,UPK2
    Uniprot AccessionO00526,Q08537
    Uniprot Entry NameUPK2_HUMAN,UPK2_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000110375
    Target ClassificationN/A

    The target: UPK2, gene name: UPK2, also named as UP2, UPII. This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.[provided by RefSeq, Sep 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.