Anti-UQCR11 monoclonal antibody

Pre-made anti-UQCR11 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to UQCR11/UQCR11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2251-Ab-1/ GM-Tg-hg-IP2251-Ab-2Anti-Human UQCR11 monoclonal antibodyHuman
GM-Tg-rg-IP2251-Ab-1/ GM-Tg-rg-IP2251-Ab-2Anti-Rat UQCR11 monoclonal antibodyRat
GM-Tg-mg-IP2251-Ab-1/ GM-Tg-mg-IP2251-Ab-2Anti-Mouse UQCR11 monoclonal antibodyMouse
GM-Tg-cynog-IP2251-Ab-1/ GM-Tg-cynog-IP2251-Ab-2Anti-Cynomolgus/ Rhesus macaque UQCR11 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2251-Ab-1/ GM-Tg-felg-IP2251-Ab-2Anti-Feline UQCR11 monoclonal antibodyFeline
GM-Tg-cang-IP2251-Ab-1/ GM-Tg-cang-IP2251-Ab-2Anti-Canine UQCR11 monoclonal antibodyCanine
GM-Tg-bovg-IP2251-Ab-1/ GM-Tg-bovg-IP2251-Ab-2Anti-Bovine UQCR11 monoclonal antibodyBovine
GM-Tg-equg-IP2251-Ab-1/ GM-Tg-equg-IP2251-Ab-2Anti-Equine UQCR11 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2251-Ab-1/ GM-Tg-hg-IP2251-Ab-2; GM-Tg-rg-IP2251-Ab-1/ GM-Tg-rg-IP2251-Ab-2;
GM-Tg-mg-IP2251-Ab-1/ GM-Tg-mg-IP2251-Ab-2; GM-Tg-cynog-IP2251-Ab-1/ GM-Tg-cynog-IP2251-Ab-2;
GM-Tg-felg-IP2251-Ab-1/ GM-Tg-felg-IP2251-Ab-2; GM-Tg-cang-IP2251-Ab-1/ GM-Tg-cang-IP2251-Ab-2;
GM-Tg-bovg-IP2251-Ab-1/ GM-Tg-bovg-IP2251-Ab-2; GM-Tg-equg-IP2251-Ab-1/ GM-Tg-equg-IP2251-Ab-2
Products NameAnti-UQCR11 monoclonal antibody
Formatmab
Target NameUQCR11
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-UQCR11 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2251-Ag-1Recombinant multi-species QCR10/ UQCR11/ 0710008D09Rik protein


    Target information

    Target IDGM-IP2251
    Target NameUQCR11
    Gene ID10975,66594,690848,708396,611791,101086703,281570,100147519
    Gene Symbol and Synonyms0710008D09Rik,QCR10,UQCR,UQCR11
    Uniprot AccessionO14957,P07552
    Uniprot Entry NameQCR10_HUMAN,QCR10_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000127540
    Target ClassificationN/A

    The target: UQCR11, gene name: UQCR11, also named as 0710008D09Rik, QCR10, UQCR. This gene encodes the smallest known component of the ubiquinol-cytochrome c reductase complex, which forms part of the mitochondrial respiratory chain. The encoded protein may function as a binding factor for the iron-sulfur protein in this complex. [provided by RefSeq, Oct 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.