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Anti-USP19 monoclonal antibody
Pre-made anti-USP19 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to USP19/USP19 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2255-Ab-1/ GM-Tg-hg-IP2255-Ab-2 | Anti-Human USP19 monoclonal antibody | Human |
| GM-Tg-rg-IP2255-Ab-1/ GM-Tg-rg-IP2255-Ab-2 | Anti-Rat USP19 monoclonal antibody | Rat |
| GM-Tg-mg-IP2255-Ab-1/ GM-Tg-mg-IP2255-Ab-2 | Anti-Mouse USP19 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2255-Ab-1/ GM-Tg-cynog-IP2255-Ab-2 | Anti-Cynomolgus/ Rhesus macaque USP19 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2255-Ab-1/ GM-Tg-felg-IP2255-Ab-2 | Anti-Feline USP19 monoclonal antibody | Feline |
| GM-Tg-cang-IP2255-Ab-1/ GM-Tg-cang-IP2255-Ab-2 | Anti-Canine USP19 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2255-Ab-1/ GM-Tg-bovg-IP2255-Ab-2 | Anti-Bovine USP19 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2255-Ab-1/ GM-Tg-equg-IP2255-Ab-2 | Anti-Equine USP19 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2255-Ab-1/ GM-Tg-hg-IP2255-Ab-2; GM-Tg-rg-IP2255-Ab-1/ GM-Tg-rg-IP2255-Ab-2; GM-Tg-mg-IP2255-Ab-1/ GM-Tg-mg-IP2255-Ab-2; GM-Tg-cynog-IP2255-Ab-1/ GM-Tg-cynog-IP2255-Ab-2; GM-Tg-felg-IP2255-Ab-1/ GM-Tg-felg-IP2255-Ab-2; GM-Tg-cang-IP2255-Ab-1/ GM-Tg-cang-IP2255-Ab-2; GM-Tg-bovg-IP2255-Ab-1/ GM-Tg-bovg-IP2255-Ab-2; GM-Tg-equg-IP2255-Ab-1/ GM-Tg-equg-IP2255-Ab-2 |
| Products Name | Anti-USP19 monoclonal antibody |
| Format | mab |
| Target Name | USP19 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-USP19 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2255-Ag-1 | Recombinant multi-species UBP19/ USP19/ ZMYND9 protein |
| ORF Viral Vector | vGMLP003356 | human USP19 Lentivirus particle |
| ORF Viral Vector | pGMLP003356 | human USP19 Lentivirus plasmid |
Target information
| Target ID | GM-IP2255 |
| Target Name | USP19 |
| Gene ID | 10869,71472,361190,707512,476627,101081789,514587,100053587 |
| Gene Symbol and Synonyms | 8430421I07Rik,USP19,ZMYND9 |
| Uniprot Accession | O94966,Q6J1Y9 |
| Uniprot Entry Name | UBP19_HUMAN,UBP19_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000172046 |
| Target Classification | N/A |
The target: USP19, gene name: USP19, also named as ZMYND9. Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This protein is a ubiquitin protein ligase and plays a role in muscle wasting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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