Anti-VRK2 monoclonal antibody

Pre-made anti-VRK2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to VRK2/VRK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2262-Ab-1/ GM-Tg-hg-IP2262-Ab-2Anti-Human VRK2 monoclonal antibodyHuman
GM-Tg-rg-IP2262-Ab-1/ GM-Tg-rg-IP2262-Ab-2Anti-Rat VRK2 monoclonal antibodyRat
GM-Tg-mg-IP2262-Ab-1/ GM-Tg-mg-IP2262-Ab-2Anti-Mouse VRK2 monoclonal antibodyMouse
GM-Tg-cynog-IP2262-Ab-1/ GM-Tg-cynog-IP2262-Ab-2Anti-Cynomolgus/ Rhesus macaque VRK2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2262-Ab-1/ GM-Tg-felg-IP2262-Ab-2Anti-Feline VRK2 monoclonal antibodyFeline
GM-Tg-cang-IP2262-Ab-1/ GM-Tg-cang-IP2262-Ab-2Anti-Canine VRK2 monoclonal antibodyCanine
GM-Tg-bovg-IP2262-Ab-1/ GM-Tg-bovg-IP2262-Ab-2Anti-Bovine VRK2 monoclonal antibodyBovine
GM-Tg-equg-IP2262-Ab-1/ GM-Tg-equg-IP2262-Ab-2Anti-Equine VRK2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2262-Ab-1/ GM-Tg-hg-IP2262-Ab-2; GM-Tg-rg-IP2262-Ab-1/ GM-Tg-rg-IP2262-Ab-2;
GM-Tg-mg-IP2262-Ab-1/ GM-Tg-mg-IP2262-Ab-2; GM-Tg-cynog-IP2262-Ab-1/ GM-Tg-cynog-IP2262-Ab-2;
GM-Tg-felg-IP2262-Ab-1/ GM-Tg-felg-IP2262-Ab-2; GM-Tg-cang-IP2262-Ab-1/ GM-Tg-cang-IP2262-Ab-2;
GM-Tg-bovg-IP2262-Ab-1/ GM-Tg-bovg-IP2262-Ab-2; GM-Tg-equg-IP2262-Ab-1/ GM-Tg-equg-IP2262-Ab-2
Products NameAnti-VRK2 monoclonal antibody
Formatmab
Target NameVRK2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-VRK2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2262-Ag-1Recombinant multi-species VRK2 protein


    Target information

    Target IDGM-IP2262
    Target NameVRK2
    Gene ID7444,69922,360991,719132,474605,101098217,523902,100052238
    Gene Symbol and Synonyms2810003O05Rik,VRK2
    Uniprot AccessionQ86Y07
    Uniprot Entry NameVRK2_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000028116
    Target ClassificationKinase

    The target: VRK2, gene name: VRK2, also named as . This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.